Nicotine absorption from e-cigarettes over 12â¯months.
Addict Behav
; 91: 102-105, 2019 04.
Article
en En
| MEDLINE
| ID: mdl-30054021
ABSTRACT
BACKGROUND:
Research indicates that, over time, exclusive e-cigarette users (vapers) gradually reduce the nicotine concentration in their e-liquid and transition to more sophisticated devices. Alongside this, consumption of e-liquid increases and constant cotinine levels are maintained.AIMS:
We aimed to confirm these observations in 27 experienced vapers tested at baseline and 12â¯months later, by measuring nicotine absorption (via salivary levels of the nicotine metabolite cotinine; ng/mL), nicotine concentrations in e-liquid (mg/mL), volume of e-liquid consumed (mL per day), device types and flavours used, both at baseline and 12â¯months.RESULTS:
Vapers reduced both their nicotine concentrations in e-liquid over 12â¯months (from 13.83â¯mg/mL at baseline to 9.91 at follow up) but significantly increased their e-liquid consumption (from 4.44 to 6.84â¯mL). No significant changes in salivary cotinine concentrations (370.88â¯ng/mL at baseline and 415.78â¯ng/mL at follow up) were observed. There was an increase in sub-ohming (using an atomiser coil with resistance of <1â¯Ω with increased power) at 12â¯months, and in the use of fruit flavoured e-liquids.CONCLUSIONS:
Our sample of experienced vapers reduced the concentration of nicotine in their e-liquid over time, but maintained their nicotine intake possibly through self-titration via more intensive puffing. Findings suggest there may be little benefit in reducing nicotine e-liquid concentration since this appears to result in higher e-liquid consumption which may incur both a financial and health cost. Gaining an understanding of underlying reasons for lowering e-liquid concentration would be a useful line of empirical enquiry.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Saliva
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Agonistas Nicotínicos
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Cotinina
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Vapeo
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Nicotina
Límite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Addict Behav
Año:
2019
Tipo del documento:
Article
País de afiliación:
Reino Unido