Structural Optimization of a Pyridinylimidazole Scaffold: Shifting the Selectivity from p38&#945; Mitogen-Activated Protein Kinase to c-Jun N-Terminal Kinase 3.

Ansideri, Francesco; Macedo, Joana T; Eitel, Michael; El-Gokha, Ahmed; Zinad, Dhafer S; Scarpellini, Camilla; Kudolo, Mark; Schollmeyer, Dieter; Boeckler, Frank M; Blaum, Bärbel S; Laufer, Stefan A; Koch, Pierre

Structural Optimization of a Pyridinylimidazole Scaffold: Shifting the Selectivity from p38α Mitogen-Activated Protein Kinase to c-Jun N-Terminal Kinase 3.

Ansideri, Francesco; Macedo, Joana T; Eitel, Michael; El-Gokha, Ahmed; Zinad, Dhafer S; Scarpellini, Camilla; Kudolo, Mark; Schollmeyer, Dieter; Boeckler, Frank M; Blaum, Bärbel S; Laufer, Stefan A; Koch, Pierre.

Afiliación

Ansideri F; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.
Macedo JT; Interfaculty Institute of Biochemistry, Eberhard Karls Universität Tübingen, Hoppe-Seyler-Straße 4, 72076 Tübingen, Germany.
Eitel M; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.
El-Gokha A; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.
Zinad DS; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.
Scarpellini C; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.
Kudolo M; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.
Schollmeyer D; Department of Organic Chemistry, Johannes Gutenberg University Mainz, Duesbergweg 10-14, D-55099 Mainz, Germany.
Boeckler FM; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.
Blaum BS; Interfaculty Institute of Biochemistry, Eberhard Karls Universität Tübingen, Hoppe-Seyler-Straße 4, 72076 Tübingen, Germany.
Laufer SA; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.
Koch P; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.

ACS Omega ; 3(7): 7809-7831, 2018 Jul 31.

Article en En | MEDLINE | ID: mdl-30087925

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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: ACS Omega Año: 2018 Tipo del documento: Article País de afiliación: Alemania

Texto completo

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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: ACS Omega Año: 2018 Tipo del documento: Article País de afiliación: Alemania