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Transcriptomics and Transposon Mutagenesis Identify Multiple Mechanisms of Resistance to the FGFR Inhibitor AZD4547.
Kas, Sjors M; de Ruiter, Julian R; Schipper, Koen; Schut, Eva; Bombardelli, Lorenzo; Wientjens, Ellen; Drenth, Anne Paulien; de Korte-Grimmerink, Renske; Mahakena, Sunny; Phillips, Christopher; Smith, Paul D; Klarenbeek, Sjoerd; van de Wetering, Koen; Berns, Anton; Wessels, Lodewyk F A; Jonkers, Jos.
Afiliación
  • Kas SM; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • de Ruiter JR; Oncode Institute, Amsterdam, The Netherlands.
  • Schipper K; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Schut E; Oncode Institute, Amsterdam, The Netherlands.
  • Bombardelli L; Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Wientjens E; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Drenth AP; Oncode Institute, Amsterdam, The Netherlands.
  • de Korte-Grimmerink R; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Mahakena S; Oncode Institute, Amsterdam, The Netherlands.
  • Phillips C; Oncode Institute, Amsterdam, The Netherlands.
  • Smith PD; Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Klarenbeek S; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • van de Wetering K; Oncode Institute, Amsterdam, The Netherlands.
  • Berns A; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Wessels LFA; Oncode Institute, Amsterdam, The Netherlands.
  • Jonkers J; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
Cancer Res ; 78(19): 5668-5679, 2018 10 01.
Article en En | MEDLINE | ID: mdl-30115694
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperazinas / Pirazoles / Benzamidas / Elementos Transponibles de ADN / Mutagénesis / Resistencia a Antineoplásicos / Receptor Tipo 2 de Factor de Crecimiento de Fibroblastos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Cancer Res Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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XML
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperazinas / Pirazoles / Benzamidas / Elementos Transponibles de ADN / Mutagénesis / Resistencia a Antineoplásicos / Receptor Tipo 2 de Factor de Crecimiento de Fibroblastos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Cancer Res Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos