The Use and Indication of Ivabradine in Heart Failure.
Heart Fail Clin
; 14(4): 493-500, 2018 Oct.
Article
en En
| MEDLINE
| ID: mdl-30266358
ABSTRACT
Heart failure affects more than 6 million people in the United States each year and the prognosis is poor. The elevated heart rate in heart failure patents is problematic, because it increases myocardial oxygen demand, decreases myocardial perfusion, and has been associated with increased rates of hospitalization and mortality. For these reasons, heart rate reduction has long been a therapeutic target in heart failure. Ivabradine is a selective inhibitor of the sinoatrial pacemaker modulating "f-current" (If) and provides heart rate reduction that can be beneficial in patients with heart failure with reduced ejection fraction.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Benzazepinas
/
Insuficiencia Cardíaca
/
Frecuencia Cardíaca
Límite:
Humans
Idioma:
En
Revista:
Heart Fail Clin
Año:
2018
Tipo del documento:
Article
País de afiliación:
Estados Unidos