Changes in surface tension of saliva in Down syndrome.
Eur Rev Med Pharmacol Sci
; 22(19): 6469-6474, 2018 10.
Article
en En
| MEDLINE
| ID: mdl-30338816
ABSTRACT
OBJECTIVE:
Surface tension in saliva might contribute to the maintenance of upper airway patency. The present study aimed to determine whether salivary surface tension is altered in patients with Down syndrome who are predisposed to upper airway collapse. PATIENTS ANDMETHODS:
We used the pull-off force technique to measure surface tension in samples (100 µL) of saliva collected from twenty-three male patients with Down syndrome and twenty-three healthy males (controls). p < 0.05 was considered to indicate significance.RESULTS:
Salivary surface tension was significantly lower in the patients than in the controls (57.3 ± 4.9 vs. 60.3 ± 4.7 mN/m; p = 0.039). Age and surface tension positively correlated in the patients (p = 0.001).CONCLUSIONS:
The lower surface tension of saliva in patients with Down syndrome might compensate for an anatomical predisposition towards upper airway collapsibility and other risk factors. The function of surface tension in saliva might be altered due to aging in such patients.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Saliva
/
Síndrome de Down
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Eur Rev Med Pharmacol Sci
Asunto de la revista:
FARMACOLOGIA
/
TOXICOLOGIA
Año:
2018
Tipo del documento:
Article
País de afiliación:
Japón