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Association between the intima-media thickness of the extracranial carotid arteries and metabolic syndrome in ethnic Kyrgyzs.
Kerimkulova, Alina S; Lunegova, Olga S; Mirrakhimov, Aibek E; Abilova, Saamay S; Nabiev, Malik P; Neronova, Ksenia V; Bektasheva, Erkaiym E; Toktomamatov, Ulan M; Esenbekova, Jyldyz E; Mirrakhimov, Erkin M.
Afiliación
  • Kerimkulova AS; Kyrgyz State Medical Academy named after I.K. Akhunbaev, T.Moldo street 3, Bishkek, 720040, Kyrgyz Republic. alinakg@gmail.com.
  • Lunegova OS; Kyrgyz State Medical Academy named after I.K. Akhunbaev, T.Moldo street 3, Bishkek, 720040, Kyrgyz Republic.
  • Mirrakhimov AE; Kyrgyz Society of Cardiology, Bishkek, Kyrgyz Republic.
  • Abilova SS; Kyrgyz State Medical Academy named after I.K. Akhunbaev, T.Moldo street 3, Bishkek, 720040, Kyrgyz Republic.
  • Nabiev MP; Kyrgyz State Medical Academy named after I.K. Akhunbaev, T.Moldo street 3, Bishkek, 720040, Kyrgyz Republic.
  • Neronova KV; Kyrgyz State Medical Academy named after I.K. Akhunbaev, T.Moldo street 3, Bishkek, 720040, Kyrgyz Republic.
  • Bektasheva EE; Kyrgyz State Medical Academy named after I.K. Akhunbaev, T.Moldo street 3, Bishkek, 720040, Kyrgyz Republic.
  • Toktomamatov UM; Kyrgyz State Medical Academy named after I.K. Akhunbaev, T.Moldo street 3, Bishkek, 720040, Kyrgyz Republic.
  • Esenbekova JE; Kyrgyz State Medical Academy named after I.K. Akhunbaev, T.Moldo street 3, Bishkek, 720040, Kyrgyz Republic.
  • Mirrakhimov EM; Kyrgyz State Medical Academy named after I.K. Akhunbaev, T.Moldo street 3, Bishkek, 720040, Kyrgyz Republic.
BMC Cardiovasc Disord ; 18(1): 199, 2018 10 22.
Article en En | MEDLINE | ID: mdl-30348085
BACKGROUND: It is known that atherosclerosis is the leading cause of cardiovascular disease. We aimed to study the correlation between components of metabolic syndrome (MS) and subclinical carotid atherosclerosis in a group of ethnic Kyrgyzs. METHODS: In а descriptive study we assessed 144 ethnic Kyrgyzs (69 males, 75 females) aged 36-73 years (average age 51.03 ± 8.2). All participants underwent a clinical investigation and an anthropometric evaluation (weight, height, waist circumference (WC)). Abdominal obesity (АО) was confirmed at WC ≥ 94 cm in males and ≥ 88 cm in females. Fasting plasma glucose and lipid spectrum tests were performed. An ultrasound assessment of carotid intima-media thickness (IMT) was performed using a 7.5 MHz transducer (Phillips-SD 800). RESULTS: MS was revealed in 61 (42.4%; 47.8% in men and 37.3% in women) of the investigated patients. IMT was significantly increased with the presence of MS components in males (no components vs 2 components of MS: 0.67 ± 0.007 and 0.81 ± 0.009 respectively; р < 0.05) and females (no components vs 3 components of MS: 0.63 ± 0.007 and 0.76 ± 0.01 respectively; р < 0.01). IMT trended towards an increase in the presence of a greater number of MS components in patients with and without AO (р < 0.01). In order to identify independent factors affecting IMT we carried out a multifactorial logistic regression analysis. Arterial hypertension was found to have the greatest influence on the development of MS (OR = 3.81, p < 0.0001). CONCLUSION: In the group of ethnic Kyrgyzs, a greater number of MS components, with AO or without AO, is associated with higher carotid IMT.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Arterias Carótidas / Enfermedades de las Arterias Carótidas / Síndrome Metabólico / Pueblo Asiatico / Grosor Intima-Media Carotídeo Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia / Europa Idioma: En Revista: BMC Cardiovasc Disord Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2018 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Arterias Carótidas / Enfermedades de las Arterias Carótidas / Síndrome Metabólico / Pueblo Asiatico / Grosor Intima-Media Carotídeo Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia / Europa Idioma: En Revista: BMC Cardiovasc Disord Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2018 Tipo del documento: Article