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The novel HBx mutation F30V correlates with hepatocellular carcinoma in vivo, reduces hepatitis B virus replicative efficiency and enhances anti-apoptotic activity of HBx N terminus in vitro.
Salpini, R; Surdo, M; Cortese, M F; Palumbo, G A; Carioti, L; Cappiello, G; Spanò, A; Trimoulet, P; Fleury, H; Vecchiet, J; Pasquazzi, C; Mirabelli, C; Scutari, R; Sacco, A; Alkhatib, M; Missale, G; Francioso, S; Sarmati, L; Andreoni, M; Angelico, M; Ceccherini-Silberstein, F; Levrero, M; Perno, C F; Belloni, L; Svicher, V.
Afiliación
  • Salpini R; Department of Experimental Medicine and Surgery, University of Rome 'Tor Vergata' Rome, Italy.
  • Surdo M; Department of Experimental Medicine and Surgery, University of Rome 'Tor Vergata' Rome, Italy.
  • Cortese MF; Department of Experimental Medicine and Surgery, University of Rome 'Tor Vergata' Rome, Italy; Liver Pathology Unit, Departments of Biochemistry and Microbiology, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Palumbo GA; Department of Internal Medicine-DMISM, Sapienza University, Rome, Italy.
  • Carioti L; Department of Experimental Medicine and Surgery, University of Rome 'Tor Vergata' Rome, Italy.
  • Cappiello G; 'S. Pertini Hospital', Rome, Italy.
  • Spanò A; 'S. Pertini Hospital', Rome, Italy.
  • Trimoulet P; Hôpital Pellegrin Tripode, Bordeaux, France.
  • Fleury H; Hôpital Pellegrin Tripode, Bordeaux, France.
  • Vecchiet J; 'SS Annunziata' Hospital, Chieti, Italy.
  • Pasquazzi C; 'S Andrea' Hospital, Rome, Italy.
  • Mirabelli C; Department of Experimental Medicine and Surgery, University of Rome 'Tor Vergata' Rome, Italy; University of Michigan Medical School, Ann Arbor, MI, USA.
  • Scutari R; Department of Experimental Medicine and Surgery, University of Rome 'Tor Vergata' Rome, Italy.
  • Sacco A; Department of Experimental Medicine and Surgery, University of Rome 'Tor Vergata' Rome, Italy.
  • Alkhatib M; Department of Experimental Medicine and Surgery, University of Rome 'Tor Vergata' Rome, Italy.
  • Missale G; Hospital of Parma, Parma, Italy.
  • Francioso S; Hepatology Unit, Tor Vergata University Hospital, Rome, Italy.
  • Sarmati L; Infectious Diseases Unit, Tor Vergata University Hospital, Rome, Italy.
  • Andreoni M; Infectious Diseases Unit, Tor Vergata University Hospital, Rome, Italy.
  • Angelico M; Hepatology Unit, Tor Vergata University Hospital, Rome, Italy.
  • Ceccherini-Silberstein F; Department of Experimental Medicine and Surgery, University of Rome 'Tor Vergata' Rome, Italy.
  • Levrero M; Department of Internal Medicine-DMISM, Sapienza University, Rome, Italy; INSERM U1052 - Cancer Research Centre of Lyon, 69008 Lyon, France.
  • Perno CF; Department of Experimental Medicine and Surgery, University of Rome 'Tor Vergata' Rome, Italy; Haematology and Oncohaematology, University of Milan, Italy.
  • Belloni L; Department of Internal Medicine-DMISM, Sapienza University, Rome, Italy; Centre for Life NanoSciences, IIT-Sapienza, Rome, Italy.
  • Svicher V; Department of Experimental Medicine and Surgery, University of Rome 'Tor Vergata' Rome, Italy. Electronic address: valentina.svicher@uniroma2.it.
Clin Microbiol Infect ; 25(7): 906.e1-906.e7, 2019 Jul.
Article en En | MEDLINE | ID: mdl-30472417

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Replicación Viral / Transactivadores / Virus de la Hepatitis B / Apoptosis / Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Microbiol Infect Asunto de la revista: DOENCAS TRANSMISSIVEIS / MICROBIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Italia

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Replicación Viral / Transactivadores / Virus de la Hepatitis B / Apoptosis / Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Microbiol Infect Asunto de la revista: DOENCAS TRANSMISSIVEIS / MICROBIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Italia