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The IL-1 Pathway Is Hyperactive in Hidradenitis Suppurativa and Contributes to Skin Infiltration and Destruction.
Witte-Händel, Ellen; Wolk, Kerstin; Tsaousi, Athanasia; Irmer, Marie Luise; Mößner, Rotraut; Shomroni, Orr; Lingner, Thomas; Witte, Katrin; Kunkel, Desiree; Salinas, Gabriela; Jodl, Stefan; Schmidt, Nicole; Sterry, Wolfram; Volk, Hans-Dieter; Giamarellos-Bourboulis, Evangelos J; Pokrywka, Anna; Döcke, Wolf-Dietrich; Schneider-Burrus, Sylke; Sabat, Robert.
Afiliación
  • Witte-Händel E; Interdisciplinary Group Molecular Immunopathology, Dermatology/Medical Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany; Psoriasis Research and Treatment Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Wolk K; Interdisciplinary Group Molecular Immunopathology, Dermatology/Medical Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany; Psoriasis Research and Treatment Center, Charité-Universitätsmedizin Berlin, Berlin, Germany; Berlin-Brandenburg Center for Regenerative Therapies, Charité-Universi
  • Tsaousi A; Psoriasis Research and Treatment Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Irmer ML; Psoriasis Research and Treatment Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Mößner R; Department of Dermatology, University Medical Center Göttingen, Göttingen, Germany.
  • Shomroni O; Transcriptome and Genome Core Unit, University Medical Center Göttungen, Göttingen, Germany.
  • Lingner T; Transcriptome and Genome Core Unit, University Medical Center Göttungen, Göttingen, Germany.
  • Witte K; Interdisciplinary Group Molecular Immunopathology, Dermatology/Medical Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany; Berlin-Brandenburg Center for Regenerative Therapies, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Kunkel D; Berlin-Brandenburg Center for Regenerative Therapies, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Salinas G; Transcriptome and Genome Core Unit, University Medical Center Göttungen, Göttingen, Germany.
  • Jodl S; Research and Development, Pharmaceuticals, Bayer AG, Berlin and Wuppertal, Germany.
  • Schmidt N; Research and Development, Pharmaceuticals, Bayer AG, Berlin and Wuppertal, Germany.
  • Sterry W; Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Volk HD; Berlin-Brandenburg Center for Regenerative Therapies, Charité-Universitätsmedizin Berlin, Berlin, Germany; Institute of Medical Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Giamarellos-Bourboulis EJ; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
  • Pokrywka A; Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Döcke WD; Research and Development, Pharmaceuticals, Bayer AG, Berlin and Wuppertal, Germany.
  • Schneider-Burrus S; Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Sabat R; Interdisciplinary Group Molecular Immunopathology, Dermatology/Medical Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany; Psoriasis Research and Treatment Center, Charité-Universitätsmedizin Berlin, Berlin, Germany. Electronic address: robert.sabat@charite.de.
J Invest Dermatol ; 139(6): 1294-1305, 2019 06.
Article en En | MEDLINE | ID: mdl-30528824
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Interleucina-6 / Receptores de Interleucina-1 / Hidradenitis Supurativa / Interleucina-1beta Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Invest Dermatol Año: 2019 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Interleucina-6 / Receptores de Interleucina-1 / Hidradenitis Supurativa / Interleucina-1beta Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Invest Dermatol Año: 2019 Tipo del documento: Article País de afiliación: Alemania