The effect of glutamate-induced excitotoxicity on DNA methylation in astrocytes in a new in vitro neuron-astrocyte-endothelium co-culture system.

Zhao, Hui; Sun, Pin; Fan, Tieping; Yang, Xiaohan; Zheng, Tiezheng; Sun, Changkai

The effect of glutamate-induced excitotoxicity on DNA methylation in astrocytes in a new in vitro neuron-astrocyte-endothelium co-culture system.

Zhao, Hui; Sun, Pin; Fan, Tieping; Yang, Xiaohan; Zheng, Tiezheng; Sun, Changkai.

Afiliación

Zhao H; Liaoning Provincial Key Laboratory of Cerebral Diseases, Institute for Brain Disorders, Dalian Medical University, Dalian, 116044, China; Department of Biomedical Engineering, Faculty of Electronic Information and Electrical Engineering, Dalian University of Technology, Dalian, 116024, China; Resear
Sun P; Shanghai Medical College, Fudan University, Shanghai, 200000, China.
Fan T; Neurointerventional Department, Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, 116024, China.
Yang X; Liaoning Provincial Key Laboratory of Cerebral Diseases, Institute for Brain Disorders, Dalian Medical University, Dalian, 116044, China.
Zheng T; Liaoning Provincial Key Laboratory of Cerebral Diseases, Institute for Brain Disorders, Dalian Medical University, Dalian, 116044, China.
Sun C; Liaoning Provincial Key Laboratory of Cerebral Diseases, Institute for Brain Disorders, Dalian Medical University, Dalian, 116044, China; Department of Biomedical Engineering, Faculty of Electronic Information and Electrical Engineering, Dalian University of Technology, Dalian, 116024, China; Resear

Biochem Biophys Res Commun ; 508(4): 1209-1214, 2019 01 22.

Article en En | MEDLINE | ID: mdl-30558794

Asunto(s)

Astrocitos/metabolismo; Metilación de ADN/efectos de los fármacos; Células Endoteliales/metabolismo; Ácido Glutámico/toxicidad; Neuronas/metabolismo; Neurotoxinas/toxicidad; Animales; Astrocitos/efectos de los fármacos; Azacitidina/farmacología; Forma de la Célula/efectos de los fármacos; Técnicas de Cocultivo; Metilación de ADN/genética; Células Endoteliales/efectos de los fármacos; Masculino; Neuronas/efectos de los fármacos; Ratas Sprague-Dawley

Palabras clave

Astrocytes; DNA methylation; Glutamate-induced excitotoxicity; Network model

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Astrocitos / Ácido Glutámico / Metilación de ADN / Células Endoteliales / Neuronas / Neurotoxinas Límite: Animals Idioma: En Revista: Biochem Biophys Res Commun Año: 2019 Tipo del documento: Article

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