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Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2- d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5.
Nguyen, Duy; Lemos, Clara; Wortmann, Lars; Eis, Knut; Holton, Simon J; Boemer, Ulf; Moosmayer, Dieter; Eberspaecher, Uwe; Weiske, Joerg; Lechner, Christian; Prechtl, Stefan; Suelzle, Detlev; Siegel, Franziska; Prinz, Florian; Lesche, Ralf; Nicke, Barbara; Nowak-Reppel, Katrin; Himmel, Herbert; Mumberg, Dominik; von Nussbaum, Franz; Nising, Carl F; Bauser, Marcus; Haegebarth, Andrea.
Afiliación
  • Nguyen D; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Lemos C; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Wortmann L; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Eis K; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Holton SJ; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Boemer U; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Moosmayer D; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Eberspaecher U; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Weiske J; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Lechner C; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Prechtl S; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Suelzle D; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Siegel F; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Prinz F; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Lesche R; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Nicke B; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Nowak-Reppel K; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Himmel H; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Mumberg D; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • von Nussbaum F; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Nising CF; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Bauser M; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
  • Haegebarth A; Research & Development, Pharmaceuticals , Bayer AG , 13353 Berlin , Germany.
J Med Chem ; 62(2): 928-940, 2019 01 24.
Article en En | MEDLINE | ID: mdl-30563338
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piridinas / Pirimidinas / Proteína Quinasa 7 Activada por Mitógenos / Inhibidores de Proteínas Quinasas Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piridinas / Pirimidinas / Proteína Quinasa 7 Activada por Mitógenos / Inhibidores de Proteínas Quinasas Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Alemania