Synthesis and characterization of zinc oxide nanoparticles by using polyol chemistry for their antimicrobial and antibiofilm activity.
Biochem Biophys Rep
; 17: 71-80, 2019 Mar.
Article
en En
| MEDLINE
| ID: mdl-30582010
ABSTRACT
The present investigation deals with facile polyol mediated synthesis and characterization of ZnO nanoparticles and their antimicrobial activities against pathogenic microorganisms. The synthesis process was carried out by refluxing zinc acetate precursor in diethylene glycol(DEG) and triethylene glycol(TEG) in the presence and in the absence of sodium acetate for 2â¯h and 3â¯h. All synthesized ZnO nanoparticles were characterized by X-ray diffraction (XRD), UV visible spectroscopy (UV), thermogravimetric analysis (TGA), fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy(FESEM), transmission electron microscopy (TEM) and energy dispersive X-ray spectroscopy (EDX) technique. All nanoparticles showed different degree of antibacterial and antibiofilm activity against Gram-positive Staphylococcus aureus (NCIM 2654)and Gram-negative Proteus vulgaris (NCIM 2613). The antibacterial and antibiofilm activity was inversely proportional to the size of the synthesized ZnO nanoparticles. Among all prepared particles, ZnO nanoparticles with least size (~â¯15â¯nm) prepared by refluxing zinc acetate dihydrate in diethylene glycol for 3â¯h exhibited remarkable antibacterial and antibiofilm activity which may serve as potential alternatives in biomedical application.
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Banco de datos:
MEDLINE
Idioma:
En
Revista:
Biochem Biophys Rep
Año:
2019
Tipo del documento:
Article
País de afiliación:
India