AMPK-Mediated Lysosome Biogenesis in Lung Cancer Growth.
Cell Metab
; 29(2): 238-240, 2019 02 05.
Article
en En
| MEDLINE
| ID: mdl-30612899
ABSTRACT
Cancer cells must adapt to metabolic stress during tumor progression. In this issue of Cell Metabolism, Eichner et al. (2019) report that lung cancer development in genetically engineered mice requires the energy sensor AMP-activated protein kinase (AMPK). Their findings suggest that AMPK-mediated induction of lysosomal function supports cancer cell fitness, particularly during the early stages of tumorigenesis.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Proteínas Quinasas Activadas por AMP
/
Neoplasias Pulmonares
Límite:
Animals
Idioma:
En
Revista:
Cell Metab
Asunto de la revista:
METABOLISMO
Año:
2019
Tipo del documento:
Article
País de afiliación:
Estados Unidos