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Discovery of potent PTP1B inhibitors via structure-based drug design, synthesis and in vitro bioassay of Norathyriol derivatives.
Xue, Wenjie; Tian, Jinlong; Wang, Xiang Simon; Xia, Jie; Wu, Song.
Afiliación
  • Xue W; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of New Drug Research and Development, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
  • Tian J; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of New Drug Research and Development, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
  • Wang XS; Department of Pharmaceutical Sciences, College of Pharmacy, Howard University, Washington DC 20059, USA.
  • Xia J; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of New Drug Research and Development, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. Electronic address: jie.william.xia@hotmail.com.
  • Wu S; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of New Drug Research and Development, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. Electronic address: ws@imm.ac.cn.
Bioorg Chem ; 86: 224-234, 2019 05.
Article en En | MEDLINE | ID: mdl-30716620
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Xantenos / Inhibidores Enzimáticos / Proteína Tirosina Fosfatasa no Receptora Tipo 1 / Descubrimiento de Drogas Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2019 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Xantenos / Inhibidores Enzimáticos / Proteína Tirosina Fosfatasa no Receptora Tipo 1 / Descubrimiento de Drogas Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2019 Tipo del documento: Article País de afiliación: China