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Inhibition of the FAD containing ER oxidoreductin 1 (Ero1) protein by EN-460 as a strategy for treatment of multiple myeloma.
Hayes, Karen E; Batsomboon, Paratchata; Chen, Wei-Chih; Johnson, Brennan D; Becker, Andreas; Eschrich, Steven; Yang, Yan; Robart, Aaron R; Dudley, Gregory B; Geldenhuys, Werner J; Hazlehurst, Lori A.
Afiliación
  • Hayes KE; Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morganton, WV 26506, United States.
  • Batsomboon P; C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506, United States.
  • Chen WC; Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morganton, WV 26506, United States.
  • Johnson BD; Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morganton, WV 26506, United States.
  • Becker A; Moffitt Cancer Center, Tampa, FL 33612, United States.
  • Eschrich S; Moffitt Cancer Center, Tampa, FL 33612, United States.
  • Yang Y; Moffitt Cancer Center, Tampa, FL 33612, United States.
  • Robart AR; Biochemistry, School of Medicine, West Virginia University, Morgantown, WV 26506, United States.
  • Dudley GB; C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506, United States; Cancer Center, West Virginia University, Morgantown, WV 26506, United States.
  • Geldenhuys WJ; Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morganton, WV 26506, United States; C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506, United States; Cancer Center, West Virginia University, Morgantown, WV 26506, United States; Departmen
  • Hazlehurst LA; Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morganton, WV 26506, United States; Cancer Center, West Virginia University, Morgantown, WV 26506, United States. Electronic address: lahazlehurst@hsc.wvu.edu.
Bioorg Med Chem ; 27(8): 1479-1488, 2019 04 15.
Article en En | MEDLINE | ID: mdl-30850265
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oxidorreductasas / Glicoproteínas de Membrana / Apoptosis / Pirazolonas / Estrés del Retículo Endoplásmico / Imidazoles / Mieloma Múltiple Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oxidorreductasas / Glicoproteínas de Membrana / Apoptosis / Pirazolonas / Estrés del Retículo Endoplásmico / Imidazoles / Mieloma Múltiple Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos