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Precision medicine in Thailand.
Shotelersuk, Vorasuk; Tongsima, Sissades; Pithukpakorn, Manop; Eu-Ahsunthornwattana, Jakris; Mahasirimongkol, Surakameth.
Afiliación
  • Shotelersuk V; Center of Excellence for Medical Genomics, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
  • Tongsima S; Excellence Center for Medical Genetics, King Chulalongkorn Memorial Hospital, the Thai Red Cross Society, Bangkok, Thailand.
  • Pithukpakorn M; National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency, Pathum Thani, Thailand.
  • Eu-Ahsunthornwattana J; Division of Medical Genetics, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
  • Mahasirimongkol S; Siriraj Center of Research Excellence in Precision Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Am J Med Genet C Semin Med Genet ; 181(2): 245-253, 2019 06.
Article en En | MEDLINE | ID: mdl-30888117
Extraordinary advances in high throughput next generation sequencing (NGS) technology and bioinformatics are the main thrust that transforms the current state of healthcare into the era of precision medicine where clinical practice takes individual variability into account. Here, we summarize the current status of the infrastructure we have and the adoption of precision medicine in Thailand in four spheres: rare diseases, oncology, pharmacogenomics, and noncommunicable diseases. Moreover, we provide our perspectives to the future of precision medicine in Thailand, especially the manpower and ethical, legal, and social issues. We believe that with decreasing costs of NGS, increasing ability to interpret the genomic data, a greater number of actionable and available treatments, implementation of precision medicine at the public health level is not a matter of if but when.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Medicina de Precisión Límite: Humans País/Región como asunto: Asia Idioma: En Revista: Am J Med Genet C Semin Med Genet Asunto de la revista: GENETICA MEDICA Año: 2019 Tipo del documento: Article País de afiliación: Tailandia

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Medicina de Precisión Límite: Humans País/Región como asunto: Asia Idioma: En Revista: Am J Med Genet C Semin Med Genet Asunto de la revista: GENETICA MEDICA Año: 2019 Tipo del documento: Article País de afiliación: Tailandia