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Mutations That Increase the Stability of the Postfusion gp41 Conformation of the HIV-1 Envelope Glycoprotein Are Selected by both an X4 and R5 HIV-1 Virus To Escape Fusion Inhibitors Corresponding to Heptad Repeat 1 of gp41, but the gp120 Adaptive Mutations Differ between the Two Viruses.
Zhuang, Min; Vassell, Russell; Yuan, Chen; Keller, Paul W; Ling, Hong; Wang, Wei; Weiss, Carol D.
Afiliación
  • Zhuang M; Department of Microbiology, Harbin Medical University, Harbin, China zhuangm@ems.hrbmu.edu.cn carol.weiss@fda.hhs.gov.
  • Vassell R; Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Yuan C; Department of Microbiology, Harbin Medical University, Harbin, China.
  • Keller PW; Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Ling H; Department of Microbiology, Harbin Medical University, Harbin, China.
  • Wang W; Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Weiss CD; Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA zhuangm@ems.hrbmu.edu.cn carol.weiss@fda.hhs.gov.
J Virol ; 93(11)2019 06 01.
Article en En | MEDLINE | ID: mdl-30894471

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteína gp41 de Envoltorio del VIH / Proteína gp120 de Envoltorio del VIH / VIH-1 Límite: Humans Idioma: En Revista: J Virol Año: 2019 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteína gp41 de Envoltorio del VIH / Proteína gp120 de Envoltorio del VIH / VIH-1 Límite: Humans Idioma: En Revista: J Virol Año: 2019 Tipo del documento: Article