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Development of highly potent glucocorticoids for steroid-resistant severe asthma.
He, Yuanzheng; Shi, Jingjing; Nguyen, Quang Tam; You, Erli; Liu, Hongbo; Ren, Xin; Wu, Zhongshan; Li, Jianshuang; Qiu, Wenli; Khoo, Sok Kean; Yang, Tao; Yi, Wei; Sun, Feng; Xi, Zhijian; Huang, Xiaozhu; Melcher, Karsten; Min, Booki; Xu, H Eric.
Afiliación
  • He Y; Laboratory of Receptor Structure and Signaling, HIT Center for Life Science, Harbin Institute of Technology, Harbin 150001, China; ajian.he@hit.edu.cn yiwei@gzhmu.edu.cn minb@ccf.org eric.xu@vai.org.
  • Shi J; Laboratory of Structural Sciences, Van Andel Research Institute, Grand Rapids, MI 49503.
  • Nguyen QT; Van Andel Research Institute-Shanghai Institute of Materia Medica, Center for Structure and Function of Drug Targets, Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • You E; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195.
  • Liu H; Van Andel Research Institute-Shanghai Institute of Materia Medica, Center for Structure and Function of Drug Targets, Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Ren X; Center of Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503.
  • Wu Z; Department of Medicine, Lung Biology Center, University of California, San Francisco, CA 94158.
  • Li J; Department of Research and Development, Palo Alto Pharmaceuticals, Shanghai 201203, China.
  • Qiu W; Laboratory of Skeletal Biology, Van Andel Research Institute, Grand Rapids, MI 49503.
  • Khoo SK; Department of Medicine, Lung Biology Center, University of California, San Francisco, CA 94158.
  • Yang T; Department of Cell and Molecular Biology, Grand Valley State University, Grand Rapids, MI 49401.
  • Yi W; Laboratory of Skeletal Biology, Van Andel Research Institute, Grand Rapids, MI 49503.
  • Sun F; Van Andel Research Institute-Shanghai Institute of Materia Medica, Center for Structure and Function of Drug Targets, Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; ajian.he@hit.edu.cn yiwei@gzhmu.edu.cn minb@ccf.org er
  • Xi Z; Key Laboratory of Molecular Target and Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, Guangdong 511436, China.
  • Huang X; State Key Lab of Respiratory Disease, Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 511436, China.
  • Melcher K; Department of Research and Development, Palo Alto Pharmaceuticals, Shanghai 201203, China.
  • Min B; Department of Research and Development, Palo Alto Pharmaceuticals, Shanghai 201203, China.
  • Xu HE; Department of Medicine, Lung Biology Center, University of California, San Francisco, CA 94158.
Proc Natl Acad Sci U S A ; 116(14): 6932-6937, 2019 04 02.
Article en En | MEDLINE | ID: mdl-30894497
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Asma / Antiasmáticos / Desarrollo de Medicamentos / Glucocorticoides Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Asma / Antiasmáticos / Desarrollo de Medicamentos / Glucocorticoides Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2019 Tipo del documento: Article