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Positive allosteric modulation of the type 1 cannabinoid receptor reduces the signs and symptoms of Huntington's disease in the R6/2 mouse model.
Laprairie, Robert B; Bagher, Amina M; Rourke, Jillian L; Zrein, Adel; Cairns, Elizabeth A; Kelly, Melanie E M; Sinal, Christopher J; Kulkarni, Pushkar M; Thakur, Ganesh A; Denovan-Wright, Eileen M.
Afiliación
  • Laprairie RB; College of Pharmacy and Nutrition, University of Saskatchewan, Canada; Department of Pharmacology, Dalhousie University, Canada.
  • Bagher AM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, King AbdulAziz University,Saudi Arabia; Department of Pharmacology, Dalhousie University, Canada.
  • Rourke JL; Department of Pharmacology, Dalhousie University, Canada; Department of Chemistry & Biochemistry, Mount Allison University, Canada.
  • Zrein A; Department of Pharmacology, Dalhousie University, Canada.
  • Cairns EA; Department of Pharmacology, Dalhousie University, Canada.
  • Kelly MEM; Department of Pharmacology, Dalhousie University, Canada; Department of Ophthalmology and Visual Sciences, Dalhousie University, Canada.
  • Sinal CJ; Department of Pharmacology, Dalhousie University, Canada.
  • Kulkarni PM; Center for Drug Discovery, Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, USA.
  • Thakur GA; Center for Drug Discovery, Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, USA.
  • Denovan-Wright EM; Department of Pharmacology, Dalhousie University, Canada. Electronic address: emdenova@dal.ca.
Neuropharmacology ; 151: 1-12, 2019 06.
Article en En | MEDLINE | ID: mdl-30940536
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Huntington / Cuerpo Estriado / Receptor Cannabinoide CB1 / Regulación Alostérica / Agonistas de Receptores de Cannabinoides / Indoles Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Neuropharmacology Año: 2019 Tipo del documento: Article País de afiliación: Canadá
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Huntington / Cuerpo Estriado / Receptor Cannabinoide CB1 / Regulación Alostérica / Agonistas de Receptores de Cannabinoides / Indoles Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Neuropharmacology Año: 2019 Tipo del documento: Article País de afiliación: Canadá