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Histone methyltransferase SMYD2 selective inhibitor LLY-507 in combination with poly ADP ribose polymerase inhibitor has therapeutic potential against high-grade serous ovarian carcinomas.
Kukita, Asako; Sone, Kenbun; Oda, Katsutoshi; Hamamoto, Ryuji; Kaneko, Syuzo; Komatsu, Masaaki; Wada, Miku; Honjoh, Harunori; Kawata, Yoshiko; Kojima, Machiko; Oki, Shinya; Sato, Masakazu; Asada, Kayo; Taguchi, Ayumi; Miyasaka, Aki; Tanikawa, Michihiro; Nagasaka, Kazunori; Matsumoto, Yoko; Wada-Hiraike, Osamu; Osuga, Yutaka; Fujii, Tomoyuki.
Afiliación
  • Kukita A; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Sone K; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan. Electronic address: ksone5274@gmail.com.
  • Oda K; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Hamamoto R; Division of Molecular Modification and Cancer Biology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
  • Kaneko S; Division of Molecular Modification and Cancer Biology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
  • Komatsu M; Division of Molecular Modification and Cancer Biology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
  • Wada M; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Honjoh H; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Kawata Y; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Kojima M; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Oki S; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Sato M; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Asada K; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Taguchi A; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Miyasaka A; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Tanikawa M; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Nagasaka K; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Matsumoto Y; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Wada-Hiraike O; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Osuga Y; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Fujii T; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
Biochem Biophys Res Commun ; 513(2): 340-346, 2019 05 28.
Article en En | MEDLINE | ID: mdl-30955858
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Pirrolidinas / Benzamidas / N-Metiltransferasa de Histona-Lisina / Cistadenocarcinoma Seroso / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Antineoplásicos Límite: Female / Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 2019 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Pirrolidinas / Benzamidas / N-Metiltransferasa de Histona-Lisina / Cistadenocarcinoma Seroso / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Antineoplásicos Límite: Female / Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 2019 Tipo del documento: Article País de afiliación: Japón