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Neutralization of BCL-2/XL Enhances the Cytotoxicity of T-DM1 In Vivo.
Zoeller, Jason J; Vagodny, Aleksandr; Taneja, Krishan; Tan, Benjamin Y; O'Brien, Neil; Slamon, Dennis J; Sampath, Deepak; Leverson, Joel D; Bronson, Roderick T; Dillon, Deborah A; Brugge, Joan S.
Afiliación
  • Zoeller JJ; Department of Cell Biology and Ludwig Center at Harvard, Harvard Medical School, Boston, Massachusetts.
  • Vagodny A; Department of Cell Biology and Ludwig Center at Harvard, Harvard Medical School, Boston, Massachusetts.
  • Taneja K; Department of Pathology, Brigham & Women's Hospital, Boston, Massachusetts.
  • Tan BY; Department of Pathology, Brigham & Women's Hospital, Boston, Massachusetts.
  • O'Brien N; Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California.
  • Slamon DJ; Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California.
  • Sampath D; Translational Oncology, Genentech, San Francisco, California.
  • Leverson JD; Oncology Development, AbbVie, North Chicago, Illinois.
  • Bronson RT; Department of Pathology, Harvard Medical School, Boston, Massachusetts.
  • Dillon DA; Department of Pathology, Brigham & Women's Hospital, Boston, Massachusetts.
  • Brugge JS; Department of Cell Biology and Ludwig Center at Harvard, Harvard Medical School, Boston, Massachusetts. joan_brugge@hms.harvard.edu.
Mol Cancer Ther ; 18(6): 1115-1126, 2019 06.
Article en En | MEDLINE | ID: mdl-30962322
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sulfonamidas / Neoplasias de la Mama / Inmunoconjugados / Proteínas Proto-Oncogénicas c-bcl-2 / Citotoxicidad Inmunológica / Proteína bcl-X / Antineoplásicos Inmunológicos / Ado-Trastuzumab Emtansina / Compuestos de Anilina Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sulfonamidas / Neoplasias de la Mama / Inmunoconjugados / Proteínas Proto-Oncogénicas c-bcl-2 / Citotoxicidad Inmunológica / Proteína bcl-X / Antineoplásicos Inmunológicos / Ado-Trastuzumab Emtansina / Compuestos de Anilina Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2019 Tipo del documento: Article