Hesperidin-CAMKIV interaction and its impact on cell proliferation and apoptosis in the human hepatic carcinoma and neuroblastoma cells.

Naz, Huma; Tarique, Mohd; Ahamad, Shahzaib; Alajmi, Mohamed F; Hussain, Afzal; Rehman, Md Tabish; Luqman, Suaib; Hassan, Md Imtaiyaz

Naz, Huma; Tarique, Mohd; Ahamad, Shahzaib; Alajmi, Mohamed F; Hussain, Afzal; Rehman, Md Tabish; Luqman, Suaib; Hassan, Md Imtaiyaz.

Afiliación

Naz H; Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, India.
Tarique M; Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
Ahamad S; Department of Biotechnology, College of Engineering & Technology, IFTM University, Delhi Road, Moradabad, India.
Alajmi MF; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Hussain A; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Rehman MT; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Luqman S; Molecular Bioprospection Department of Biotechnology Division, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, India.
Hassan MI; Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, India.

J Cell Biochem ; 120(9): 15119-15130, 2019 09.

Article en En | MEDLINE | ID: mdl-31021496

Asunto(s)

Apoptosis; Proteína Quinasa Tipo 4 Dependiente de Calcio Calmodulina/metabolismo; Carcinoma Hepatocelular/enzimología; Carcinoma Hepatocelular/patología; Hesperidina/farmacología; Neoplasias Hepáticas/enzimología; Neoplasias Hepáticas/patología; Neuroblastoma/enzimología; Apoptosis/efectos de los fármacos; Caspasa 3/metabolismo; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; Supervivencia Celular/efectos de los fármacos; Activación Enzimática/efectos de los fármacos; Células HEK293; Hesperidina/química; Humanos; Potencial de la Membrana Mitocondrial/efectos de los fármacos; Neuroblastoma/patología; Transducción de Señal/efectos de los fármacos

Palabras clave

apoptosis; calcium/calmodulin-dependent protein kinase type IV; drug design and mitochondrial membrane potential; hesperidin; kinase inhibitors

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Apoptosis / Carcinoma Hepatocelular / Proteína Quinasa Tipo 4 Dependiente de Calcio Calmodulina / Hesperidina / Neoplasias Hepáticas / Neuroblastoma Límite: Humans Idioma: En Revista: J Cell Biochem Año: 2019 Tipo del documento: Article País de afiliación: India

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