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Female sex as a risk factor in minimally invasive direct coronary artery bypass grafting.
Gofus, Jan; Vobornik, Martin; Sorm, Zdenek; Dergel, Martin; Karalko, Mikita; Harrer, Jan; Pojar, Marek.
Afiliación
  • Gofus J; a Department of Cardiac Surgery, Faculty of Medicine and University Hospital in Hradec Kralove , Charles University , Hradec Kralove , Czech Republic.
  • Vobornik M; a Department of Cardiac Surgery, Faculty of Medicine and University Hospital in Hradec Kralove , Charles University , Hradec Kralove , Czech Republic.
  • Sorm Z; a Department of Cardiac Surgery, Faculty of Medicine and University Hospital in Hradec Kralove , Charles University , Hradec Kralove , Czech Republic.
  • Dergel M; a Department of Cardiac Surgery, Faculty of Medicine and University Hospital in Hradec Kralove , Charles University , Hradec Kralove , Czech Republic.
  • Karalko M; a Department of Cardiac Surgery, Faculty of Medicine and University Hospital in Hradec Kralove , Charles University , Hradec Kralove , Czech Republic.
  • Harrer J; a Department of Cardiac Surgery, Faculty of Medicine and University Hospital in Hradec Kralove , Charles University , Hradec Kralove , Czech Republic.
  • Pojar M; a Department of Cardiac Surgery, Faculty of Medicine and University Hospital in Hradec Kralove , Charles University , Hradec Kralove , Czech Republic.
Scand Cardiovasc J ; 53(3): 141-147, 2019 Jun.
Article en En | MEDLINE | ID: mdl-31030573
Objectives. Female sex has been generally accepted as a risk factor for short-term mortality and adverse events in surgical myocardial revascularization. However, there have been no data published yet about sex differences in minimally invasive settings. The aim of our study was to analyse short- and long- term outcomes of minimally invasive direct coronary artery bypass grafting (MIDCAB) in terms of sex comparison. Design. We retrospectively analysed the in-hospital data of all patients (n = 384) undergoing MIDCAB at our department in years 2006-2016. Subsequently, the data were enriched by long-term outcomes from national registries. Results. There were 96 women in our group (25%). Females were significantly older (67.1 vs 63.8 years; p < .01) and were more often diabetic (43.8% vs. 31.8%; p < .01). Surgery time was longer in females (160 vs 155 min; p = .02), and also the need for blood transfusion (19.8% vs 10.4%; p = .02) and wound complications (15.6% vs 2.4%; p < .001) were more frequent in women. After multivariate analysis, the wound complications risk (p < .001) and longer surgery times (p < .01) remained associated with sex. All-cause in-hospital mortality (2.1% vs 0.7%; p = .26), long-term mortality (p = .73), and the risk of coronary intervention post-operatively (p = .16) were the same in both sexes. Higher incidence of cardiac cause of death in women was observed from long-term aspect (69.6% vs 38.7%; p = .01). However, after adjustment it lost its significance. Conclusions. Female sex is not connected with higher risk of mortality or other major events in MIDCAB. Wound healing complications remain the leading attribute associated with female sex.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Enfermedad de la Arteria Coronaria / Puente de Arteria Coronaria Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Scand Cardiovasc J Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: República Checa

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Enfermedad de la Arteria Coronaria / Puente de Arteria Coronaria Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Scand Cardiovasc J Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: República Checa