Study of kidney morphologic and structural changes related to different ischemia times and types of clamping of the renal vascular pedicle.
Int Braz J Urol
; 45(4): 754-762, 2019.
Article
en En
| MEDLINE
| ID: mdl-31184454
ABSTRACT
PURPOSE:
This study aimed to study morphological and renal structural changes in relation to different ischemic times and types of renal vascular pedicle clamping.METHODS:
Sixteen pigs were divided into two groups (n = 8) Group AV - unilateral clamping of the renal artery and vein and Group A - unilateral clamping of the renal artery only, both with the contralateral kidney used as control. Serial biopsies were performed at 0, 10, 20, 30, 40, 50, 60, 70, 80, and 90 minutes after clamping.RESULTS:
there is a correlation between the occurrence of renal damage as a function of time (p < 0.001), with a higher frequency of Group A lesions for cellular alterations (vascular congestion and edema, interstitial inflammatory infiltrate, interstitial hemorrhage and cell degeneration), with the exception of in the formation of pigmented cylinders that were evidenced only in the AV Group.CONCLUSION:
the number of lesions derived from ischemia is associated with the duration of the insult, there is a significant difference between the types of clamping, and the AV Group presented a lower frequency of injuries than Group A. The safety time found for Group A was 10 minutes and for Group AV 20 minutes.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Arteria Renal
/
Venas Renales
/
Isquemia
/
Riñón
/
Nefrectomía
Tipo de estudio:
Evaluation_studies
Límite:
Animals
Idioma:
En
Revista:
Int Braz J Urol
Asunto de la revista:
UROLOGIA
Año:
2019
Tipo del documento:
Article
País de afiliación:
Brasil