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Lipidoid-polymer hybrid nanoparticles loaded with TNF siRNA suppress inflammation after intra-articular administration in a murine experimental arthritis model.
Jansen, Manon A A; Klausen, Lasse H; Thanki, Kaushik; Lyngsø, Jeppe; Skov Pedersen, Jan; Franzyk, Henrik; Nielsen, Hanne M; van Eden, Willem; Dong, Mingdong; Broere, Femke; Foged, Camilla; Zeng, Xianghui.
Afiliación
  • Jansen MAA; Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
  • Klausen LH; Interdisciplinary Nanoscience Center, Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus C, Denmark.
  • Thanki K; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen Ø, Denmark.
  • Lyngsø J; Interdisciplinary Nanoscience Center, Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus C, Denmark; Department of Chemistry, Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus C, Denmark.
  • Skov Pedersen J; Interdisciplinary Nanoscience Center, Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus C, Denmark; Department of Chemistry, Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus C, Denmark.
  • Franzyk H; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, DK-2100 Copenhagen Ø, Denmark.
  • Nielsen HM; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen Ø, Denmark.
  • van Eden W; Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
  • Dong M; Interdisciplinary Nanoscience Center, Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus C, Denmark.
  • Broere F; Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands; Department of Clinical Sciences of Companion Animals, Faculty Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
  • Foged C; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen Ø, Denmark. Electronic address: camilla.foged@sund.ku.dk.
  • Zeng X; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen Ø, Denmark. Electronic address: zengxh@ynu.edu.cn.
Eur J Pharm Biopharm ; 142: 38-48, 2019 Sep.
Article en En | MEDLINE | ID: mdl-31199978
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Polímeros / Artritis Experimental / Factor de Necrosis Tumoral alfa / ARN Interferente Pequeño / Nanopartículas / Inflamación / Lípidos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Eur J Pharm Biopharm Asunto de la revista: FARMACIA / FARMACOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Polímeros / Artritis Experimental / Factor de Necrosis Tumoral alfa / ARN Interferente Pequeño / Nanopartículas / Inflamación / Lípidos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Eur J Pharm Biopharm Asunto de la revista: FARMACIA / FARMACOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos