Self-Assembled Columnar Triazole Quartets: An Example of Synergistic Hydrogen-Bonding/Anion-π Interactions.
Angew Chem Int Ed Engl
; 58(35): 12037-12042, 2019 08 26.
Article
en En
| MEDLINE
| ID: mdl-31225679
ABSTRACT
The self-assembly of triazole amphiphiles was examined in solution, the solid state, and in bilayer membranes. Single-crystal X-ray diffraction experiments show that stacked protonated triazole quartets (T4 ) are stabilized by multiple strong interactions with two anions. Hydrogen bonding/ion pairing of the anions are combined with anion-π recognition to produce columnar architectures. In bilayer membranes, low transport activity is observed when the T4 channels are operated as H+ /X- translocators, but higher transport activity is observed for X- in the presence of the K+ -carrier valinomycin. These self-assembled superstructures, presenting intriguing structural behaviors such as directionality, and strong anion encapsulation by hydrogen bonding supported by vicinal anion-π interactions can serve as artificial supramolecular channels for transporting anions across lipid bilayer membranes.
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MEDLINE
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En
Revista:
Angew Chem Int Ed Engl
Año:
2019
Tipo del documento:
Article
País de afiliación:
China