In Search of Panacea-Review of Recent Studies Concerning Nature-Derived Anticancer Agents.
Nutrients
; 11(6)2019 Jun 25.
Article
en En
| MEDLINE
| ID: mdl-31242602
ABSTRACT
Cancers are one of the leading causes of deaths affecting millions of people around the world, therefore they are currently a major public health problem. The treatment of cancer is based on surgical resection, radiotherapy, chemotherapy or immunotherapy, much of which is often insufficient and cause serious, burdensome and undesirable side effects. For many years, assorted secondary metabolites derived from plants have been used as antitumor agents. Recently, researchers have discovered a large number of new natural substances which can effectively interfere with cancer cells' metabolism. The most famous groups of these compounds are topoisomerase and mitotic inhibitors. The aim of the latest research is to characterize natural compounds found in many common foods, especially by means of their abilities to regulate cell cycle, growth and differentiation, as well as epigenetic modulation. In this paper, we focus on a review of recent discoveries regarding nature-derived anticancer agents.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Dieta
/
Antimitóticos
/
Inhibidores de Topoisomerasa
/
Neoplasias
/
Antineoplásicos Fitogénicos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Nutrients
Año:
2019
Tipo del documento:
Article
País de afiliación:
Polonia