The efficacy of a computer alert programme for increasing HBV screening rates before starting immunosuppressive therapy.
Acta Gastroenterol Belg
; 82(2): 279-284, 2019.
Article
en En
| MEDLINE
| ID: mdl-31314189
ABSTRACT
BACKGROUND AND AIM:
Hepatitis B Virus (HBV) screening before starting immunosuppressive treatment is of vital importance in order to prevent HBV reactivation and its associated clinical consequences. Despite all recommendations by international organizations, screening rates are far below desired. The aim of this study was to assess the efficacy of a computer alert programme 'HBVision' for increasing HBV screening rates. MATERIAL ANDMETHODS:
'HBVision' identifies patients at risk of HBV reactivation by specific ICD-10 codes and immunosuppressive medication reports and sends sequential alert messages to screen for HBsAg, anti-HBc IgG and consult a specialist if one of them is positive. The demographic variables, treatment protocols, HBV screening and consultation rates of oncology and hematology patients who started immunosuppressive treatments within one year before (control group) and after "HBVision" (study group) were retrospectively compared.RESULTS:
HBsAg and anti-HBc IgG screening rates (68.6% and 13.1%, respectively) were significantly higher in the study group (n=602) compared to control group (n=815) (55% and 4.3%, respectively) (p<0.001, for both). Subgroup analysis revealed significant improvements in the screening rates of HBsAg (65.8%) and anti-HBc IgG (5.1%) in oncology patients (p<0.001), anti-HBc IgG (89.1%) in hematology patients (p<0.001).CONCLUSION:
The computer alert programme significantly increased HBV screening rates before starting immunosuppressive treatments, however the results were still below ideal. Additional efforts, such as modifying the computer programme according to feedbacks, are probably needed.Palabras clave
Buscar en Google
Banco de datos:
MEDLINE
Asunto principal:
Activación Viral
/
Virus de la Hepatitis B
/
Hepatitis B
/
Antígenos de Superficie de la Hepatitis B
/
Inmunosupresores
Tipo de estudio:
Diagnostic_studies
/
Guideline
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Límite:
Humans
Idioma:
En
Revista:
Acta Gastroenterol Belg
Año:
2019
Tipo del documento:
Article
País de afiliación:
Turquía