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Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ.
Liu, Chang; Chikina, Maria; Deshpande, Rahul; Menk, Ashley V; Wang, Ting; Tabib, Tracy; Brunazzi, Erin A; Vignali, Kate M; Sun, Ming; Stolz, Donna B; Lafyatis, Robert A; Chen, Wei; Delgoffe, Greg M; Workman, Creg J; Wendell, Stacy G; Vignali, Dario A A.
Afiliación
  • Liu C; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
  • Chikina M; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • Deshpande R; Health Sciences Metabolomics and Lipidomics Core, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Menk AV; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA.
  • Wang T; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15224, USA.
  • Tabib T; Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • Brunazzi EA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
  • Vignali KM; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
  • Sun M; Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • Stolz DB; Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • Lafyatis RA; Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • Chen W; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15224, USA.
  • Delgoffe GM; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA.
  • Workman CJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
  • Wendell SG; Health Sciences Metabolomics and Lipidomics Core, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Pharmacology and Chemical Biology, Clinical Translational Science Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA. Electronic address: dvignali@pitt.edu.
Immunity ; 51(2): 381-397.e6, 2019 08 20.
Article en En | MEDLINE | ID: mdl-31350177
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T Reguladores / Linfocitos T CD8-positivos / Proteína 1 de Unión a los Elementos Reguladores de Esteroles / Macrófagos / Melanoma / Neoplasias Experimentales Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T Reguladores / Linfocitos T CD8-positivos / Proteína 1 de Unión a los Elementos Reguladores de Esteroles / Macrófagos / Melanoma / Neoplasias Experimentales Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos