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R2-8018 reduces the proliferation and migration of non-small cell lung cancer cells by disturbing transactivation between M3R and EGFR.
Lan, Liting; Wang, Hua; Yang, Rui; Liu, Fengqi; Bi, Qingshang; Wang, Shiqi; Wei, Xiaoli; Yan, Haitao; Su, Ruibin.
Afiliación
  • Lan L; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Key Laboratory of Neuropsychopharmacology, Department of Biochemical Pharmacology, Beijing Institute of Pharmacology and Toxicology, 27th Taiping Road, Beijing 100850, China.
  • Wang H; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Key Laboratory of Neuropsychopharmacology, Department of Biochemical Pharmacology, Beijing Institute of Pharmacology and Toxicology, 27th Taiping Road, Beijing 100850, China; 69242 Force Health Center, No. 1, Hongxing Road, Turp
  • Yang R; National Institutes for Food and Drug Control, No. 31, Huatuo Road, Daxing District, Beijing 102629, China.
  • Liu F; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Key Laboratory of Neuropsychopharmacology, Department of Biochemical Pharmacology, Beijing Institute of Pharmacology and Toxicology, 27th Taiping Road, Beijing 100850, China; Department of Medical Laboratory, Changzhi Medical Co
  • Bi Q; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Key Laboratory of Neuropsychopharmacology, Department of Biochemical Pharmacology, Beijing Institute of Pharmacology and Toxicology, 27th Taiping Road, Beijing 100850, China; Department of Medical Laboratory, Changzhi Medical Co
  • Wang S; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Key Laboratory of Neuropsychopharmacology, Department of Biochemical Pharmacology, Beijing Institute of Pharmacology and Toxicology, 27th Taiping Road, Beijing 100850, China; Center for Drug Evaluation, NMPA. No. 128, Jianguo Ro
  • Wei X; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Key Laboratory of Neuropsychopharmacology, Department of Biochemical Pharmacology, Beijing Institute of Pharmacology and Toxicology, 27th Taiping Road, Beijing 100850, China.
  • Yan H; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Key Laboratory of Neuropsychopharmacology, Department of Biochemical Pharmacology, Beijing Institute of Pharmacology and Toxicology, 27th Taiping Road, Beijing 100850, China. Electronic address: yanht7809@aliyun.com.
  • Su R; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Key Laboratory of Neuropsychopharmacology, Department of Biochemical Pharmacology, Beijing Institute of Pharmacology and Toxicology, 27th Taiping Road, Beijing 100850, China. Electronic address: ruibinsu@126.com.
Life Sci ; 234: 116742, 2019 Oct 01.
Article en En | MEDLINE | ID: mdl-31401315
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Movimiento Celular / Carcinoma de Pulmón de Células no Pequeñas / Receptor Muscarínico M3 / Proliferación Celular / Neoplasias Pulmonares / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Life Sci Año: 2019 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Movimiento Celular / Carcinoma de Pulmón de Células no Pequeñas / Receptor Muscarínico M3 / Proliferación Celular / Neoplasias Pulmonares / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Life Sci Año: 2019 Tipo del documento: Article País de afiliación: China