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Comparison of the urinary glucose excretion contributions of SGLT2 and SGLT1: A quantitative systems pharmacology analysis in healthy individuals and patients with type 2 diabetes treated with SGLT2 inhibitors.
Yakovleva, Tatiana; Sokolov, Victor; Chu, Lulu; Tang, Weifeng; Greasley, Peter J; Peilot Sjögren, Helena; Johansson, Susanne; Peskov, Kirill; Helmlinger, Gabriel; Boulton, David W; Penland, Robert C.
Afiliación
  • Yakovleva T; M&S Decisions, Moscow, Russian Federation.
  • Sokolov V; M&S Decisions, Moscow, Russian Federation.
  • Chu L; Clinical Pharmacology & Safety Sciences, R&D BioPharmaceuticals, AstraZeneca, Waltham, Massachusetts.
  • Tang W; Clinical Pharmacology & Safety Sciences, R&D BioPharmaceuticals, AstraZeneca, Gaithersburg, Maryland.
  • Greasley PJ; CVRM, R&D BioPharmaceuticals, AstraZeneca, Gothenburg, Sweden.
  • Peilot Sjögren H; Discovery Biology, Discovery Sciences, R&D BioPharmaceuticals, AstraZeneca, Gothenburg, Sweden.
  • Johansson S; Clinical Pharmacology & Safety Sciences, R&D BioPharmaceuticals, AstraZeneca, Gothenburg, Sweden.
  • Peskov K; M&S Decisions, Moscow, Russian Federation.
  • Helmlinger G; I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.
  • Boulton DW; Clinical Pharmacology & Safety Sciences, R&D BioPharmaceuticals, AstraZeneca, Waltham, Massachusetts.
  • Penland RC; Clinical Pharmacology & Safety Sciences, R&D BioPharmaceuticals, AstraZeneca, Gaithersburg, Maryland.
Diabetes Obes Metab ; 21(12): 2684-2693, 2019 12.
Article en En | MEDLINE | ID: mdl-31423699
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Transportador 1 de Sodio-Glucosa / Transportador 2 de Sodio-Glucosa / Inhibidores del Cotransportador de Sodio-Glucosa 2 / Glucosuria Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Diabetes Obes Metab Asunto de la revista: ENDOCRINOLOGIA / METABOLISMO Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Transportador 1 de Sodio-Glucosa / Transportador 2 de Sodio-Glucosa / Inhibidores del Cotransportador de Sodio-Glucosa 2 / Glucosuria Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Diabetes Obes Metab Asunto de la revista: ENDOCRINOLOGIA / METABOLISMO Año: 2019 Tipo del documento: Article