Metilación de ADN; Nucleósidos de Pirimidina/química; Ribosa/química; ADN/química; Gases/química; Modelos Moleculares; Protones; ARN/química; Espectrometría de Masa por Ionización de Electrospray

2'-O-methyl-5-methyluridine (Thdm); 2'-O-methylation; 2'-O-methylcytidine (Cydm); 2'-O-methyluridine (Urdm); 5-Methyluridine; Cytidine (Cyd); Cytosine (Cyt); Density functional theory (DFT); Electronic structure calculations; Electrospray ionization (ESI); Energy-resolved collision-induced dissociation (ER-CID); Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS); Gas-phase conformation; Glycosidic bond stability; Hydrogen-bonding interactions; Hydrogen-stretching region; IR fingerprint region; IR spectrum; IRMPD spectrum; Infrared multiple photon dissociation (IRMPD) action spectroscopy; Nucleobase; Nucleobase orientation; Nucleoside; Nucleoside modification; Protonation; Pyrimidine nucleosides; Quadrupole ion trap mass spectrometer (QIT MS); Simulated annealing; Sugar puckering; Survival yield analysis; Tandem mass spectrometry; Thymidine (Thd); Thymine (Thy); Uracil (Ura); Uridine (Urd)