Physicochemical properties and bioactivities of original and Se-enriched polysaccharides with different molecular weights extracted from Pleurotus ostreatus.
Int J Biol Macromol
; 141: 150-160, 2019 Dec 01.
Article
en En
| MEDLINE
| ID: mdl-31487514
ABSTRACT
Three polysaccharides (WZP1, WZP2, WZP3) and their Se-enriched products (SeWZP1, SeWZP2 and SeWZP3) were obtained from Pleurotus ostreatus using a simple, rapid method and HNO3-Na2SeO3 method, respectively. The molecular weight distribution profiles of all samples except SeWZP2 showed double peaks. The average molecular weights (Mw) of WZP1-3 were 48.6â¯kDa, 20.2â¯kDa and 11.8â¯kDa, respectively, and of SeWZP1-3 were 19.6â¯kDa, 37.7â¯kDa, 14.5â¯kDa, respectively. The complexity of monosaccharide composition of WZP1-3 was inversely proportional to the ethanol concentration used in the ethanol precipitation process. Additionally, the results of biological activity tests indicated that α-glucosidase inhibitory activity of WZP1-3 was related to the molecular weight and the monosaccharide composition complexity. The selenized modification can improve the α-glucosidase-inhibiting, hydroxyl radical-scavenging activity of P. ostreatus polysaccharides. Therefore, by improving their bioactivities by selenization, the polysaccharides of P. ostreatus could be utilized as a natural health food supplement.
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Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Depuradores de Radicales Libres
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Pleurotus
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Polisacáridos Fúngicos
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Inhibidores de Glicósido Hidrolasas
Idioma:
En
Revista:
Int J Biol Macromol
Año:
2019
Tipo del documento:
Article
País de afiliación:
China