Aminonaphthalimide hybrids of mitoxantrone and amonafide as anticancer and fluorescent cellular imaging agents.

Johnson, Alex D; Zammit, Rodrianne; Vella, Jasmine; Valentino, Mario; Buhagiar, Joseph A; Magri, David C

Johnson, Alex D; Zammit, Rodrianne; Vella, Jasmine; Valentino, Mario; Buhagiar, Joseph A; Magri, David C.

Afiliación

Johnson AD; Department of Chemistry, Faculty of Science, University of Malta, Msida, MSD 2080, Malta.
Zammit R; Department of Biology, Faculty of Science, University of Malta, Msida, MSD 2080, Malta.
Vella J; Department of Physiology and Biochemistry, Faculty of Medicine & Surgery, University of Malta, Msida, MSD 2080, Malta.
Valentino M; Department of Physiology and Biochemistry, Faculty of Medicine & Surgery, University of Malta, Msida, MSD 2080, Malta.
Buhagiar JA; Department of Biology, Faculty of Science, University of Malta, Msida, MSD 2080, Malta.
Magri DC; Department of Chemistry, Faculty of Science, University of Malta, Msida, MSD 2080, Malta. Electronic address: david.magri@um.edu.mt.

Bioorg Chem ; 93: 103287, 2019 12.

Article en En | MEDLINE | ID: mdl-31561011

Asunto(s)

Antineoplásicos/química; Mitoxantrona/química; Naftalimidas/química; Ftalimidas/química; Adenina; Antineoplásicos/síntesis química; Antineoplásicos/farmacología; Apoptosis/efectos de los fármacos; Línea Celular Tumoral; Colorantes Fluorescentes/química; Humanos; Microscopía Fluorescente; Organofosfonatos; Ftalimidas/síntesis química; Ftalimidas/farmacología; Espectrometría de Fluorescencia

Palabras clave

Aminonaphthalimide; Amonafide; Apoptosis; Cytotoxicity; Fluorescence; Mitoxantrone

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ftalimidas / Mitoxantrona / Naftalimidas / Antineoplásicos Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2019 Tipo del documento: Article País de afiliación: Malta

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