Independent association of low IFN&#955;1 gene expression and type I IFN score/IFN&#955;1 ratio with obstetric manifestations and triple antiphospholipid antibody positivity in primary antiphospholipid syndrome.

Flessa, Christina-Maria; Vlachiotis, Stelios; Nezos, Adrianos; Andreakos, Evangelos; Mavragani, Clio P; Tektonidou, Maria G

Independent association of low IFNλ1 gene expression and type I IFN score/IFNλ1 ratio with obstetric manifestations and triple antiphospholipid antibody positivity in primary antiphospholipid syndrome.

Flessa, Christina-Maria; Vlachiotis, Stelios; Nezos, Adrianos; Andreakos, Evangelos; Mavragani, Clio P; Tektonidou, Maria G.

Afiliación

Flessa CM; Department of Physiology, National and Kapodistrian University of Athens, Athens, Greece; First Department of Propaedeutic Internal Medicine, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Vlachiotis S; Laboratory of Immunobiology, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, 11527 Athens, Greece.
Nezos A; Department of Physiology, National and Kapodistrian University of Athens, Athens, Greece.
Andreakos E; Laboratory of Immunobiology, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, 11527 Athens, Greece.
Mavragani CP; Department of Physiology, National and Kapodistrian University of Athens, Athens, Greece; Joint Academic Rheumatology Program, National and Kapodistrian University of Athens, Athens, Greece.
Tektonidou MG; First Department of Propaedeutic Internal Medicine, Medical School, National and Kapodistrian University of Athens, Athens, Greece; Joint Academic Rheumatology Program, National and Kapodistrian University of Athens, Athens, Greece. Electronic address: mtektonidou@med.uoa.gr.

Clin Immunol ; 209: 108265, 2019 12.

Article en En | MEDLINE | ID: mdl-31639447

Asunto(s)

Anticuerpos Antifosfolípidos/genética; Síndrome Antifosfolípido/genética; Expresión Génica/genética; Interferón Tipo I/genética; Interferones/genética; Interleucinas/genética; Adulto; Biomarcadores/metabolismo; Femenino; Humanos; Leucocitos Mononucleares; Lupus Eritematoso Sistémico/genética; Masculino

Palabras clave

Antiphospholipid syndrome; IFNλ1 gene expression; Obstetric manifestations; Systemic lupus erythematosus; Triple antiphospholipid antibody positivity; Type I IFN score

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Interferón Tipo I / Expresión Génica / Interleucinas / Interferones / Síndrome Antifosfolípido / Anticuerpos Antifosfolípidos Tipo de estudio: Risk_factors_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Clin Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Grecia

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