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eIF4A inhibition circumvents uncontrolled DNA replication mediated by 4E-BP1 loss in pancreatic cancer.
Müller, David; Shin, Sauyeun; Goullet de Rugy, Théo; Samain, Rémi; Baer, Romain; Strehaiano, Manon; Masvidal-Sanz, Laia; Guillermet-Guibert, Julie; Jean, Christine; Tsukumo, Yoshinori; Sonenberg, Nahum; Marion, Frédéric; Guilbaud, Nicolas; Hoffmann, Jean-Sébastien; Larsson, Ola; Bousquet, Corinne; Pyronnet, Stéphane; Martineau, Yvan.
Afiliación
  • Müller D; Cancer Research Center of Toulouse (CRCT), INSERM UMR 1037, University Toulouse III Paul Sabatier, ERL5294 CNRS, Toulouse, France.
  • Shin S; Equipe Labellisée Ligue Contre le Cancer and Laboratoire d'Excellence Toulouse Cancer (TOUCAN), Toulouse, France.
  • Goullet de Rugy T; Cancer Research Center of Toulouse (CRCT), INSERM UMR 1037, University Toulouse III Paul Sabatier, ERL5294 CNRS, Toulouse, France.
  • Samain R; Equipe Labellisée Ligue Contre le Cancer and Laboratoire d'Excellence Toulouse Cancer (TOUCAN), Toulouse, France.
  • Baer R; Cancer Research Center of Toulouse (CRCT), INSERM UMR 1037, University Toulouse III Paul Sabatier, ERL5294 CNRS, Toulouse, France.
  • Strehaiano M; Cancer Research Center of Toulouse (CRCT), INSERM UMR 1037, University Toulouse III Paul Sabatier, ERL5294 CNRS, Toulouse, France.
  • Masvidal-Sanz L; Equipe Labellisée Ligue Contre le Cancer and Laboratoire d'Excellence Toulouse Cancer (TOUCAN), Toulouse, France.
  • Guillermet-Guibert J; Cancer Research Center of Toulouse (CRCT), INSERM UMR 1037, University Toulouse III Paul Sabatier, ERL5294 CNRS, Toulouse, France.
  • Jean C; Cancer Research Center of Toulouse (CRCT), INSERM UMR 1037, University Toulouse III Paul Sabatier, ERL5294 CNRS, Toulouse, France.
  • Tsukumo Y; Equipe Labellisée Ligue Contre le Cancer and Laboratoire d'Excellence Toulouse Cancer (TOUCAN), Toulouse, France.
  • Sonenberg N; Department of Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Solna, Sweden.
  • Marion F; Cancer Research Center of Toulouse (CRCT), INSERM UMR 1037, University Toulouse III Paul Sabatier, ERL5294 CNRS, Toulouse, France.
  • Guilbaud N; Cancer Research Center of Toulouse (CRCT), INSERM UMR 1037, University Toulouse III Paul Sabatier, ERL5294 CNRS, Toulouse, France.
  • Hoffmann JS; Equipe Labellisée Ligue Contre le Cancer and Laboratoire d'Excellence Toulouse Cancer (TOUCAN), Toulouse, France.
  • Larsson O; Molecular Diagnostics Section, Division of Molecular Target and Gene Therapy Products, National Institute of Health Sciences, Tokyo, Japan.
  • Bousquet C; Department of Biochemistry and Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.
  • Pyronnet S; Research and Development Center, Laboratoires Pierre Fabre, Toulouse, France.
  • Martineau Y; Research and Development Center, Laboratoires Pierre Fabre, Toulouse, France.
JCI Insight ; 4(21)2019 11 01.
Article en En | MEDLINE | ID: mdl-31672935
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Proteínas de Ciclo Celular / Carcinoma Ductal Pancreático / Factor 4A Eucariótico de Iniciación / Proteínas Adaptadoras Transductoras de Señales / Replicación del ADN Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: JCI Insight Año: 2019 Tipo del documento: Article País de afiliación: Francia
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Proteínas de Ciclo Celular / Carcinoma Ductal Pancreático / Factor 4A Eucariótico de Iniciación / Proteínas Adaptadoras Transductoras de Señales / Replicación del ADN Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: JCI Insight Año: 2019 Tipo del documento: Article País de afiliación: Francia