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A high yielding IFNAR1 ECD mammalian expression process for use in autoimmune disease drug development.
Kittinger, Caroline; Barnes, Arnita; Hunter, Alan; Machiesky, LeeAnn; Phipps, Sandrina; Shannon, Anthony; Stadelman, Robert; Wilson, Susan; O'Connor, Ellen.
Afiliación
  • Kittinger C; Process Purification Sciences, AstraZeneca, One MedImmune Way, Gaithersburg, MD, 20878, USA. Electronic address: kittingerc@medimmune.com.
  • Barnes A; Antibody Discovery and Protein Engineering, AstraZeneca, One MedImmune Way, Gaithersburg, MD, 20878, USA.
  • Hunter A; Process Purification Sciences, AstraZeneca, One MedImmune Way, Gaithersburg, MD, 20878, USA.
  • Machiesky L; Analytical Sciences, AstraZeneca, One MedImmune Way, Gaithersburg, MD, 20878, USA.
  • Phipps S; Antibody Discovery and Protein Engineering, AstraZeneca, One MedImmune Way, Gaithersburg, MD, 20878, USA.
  • Shannon A; Analytical Sciences, AstraZeneca, One MedImmune Way, Gaithersburg, MD, 20878, USA.
  • Stadelman R; Cell Culture and Fermentation Sciences, AstraZeneca, One MedImmune Way, Gaithersburg, MD, 20878, USA.
  • Wilson S; Antibody Discovery and Protein Engineering, AstraZeneca, One MedImmune Way, Gaithersburg, MD, 20878, USA.
  • O'Connor E; Process Purification Sciences, AstraZeneca, One MedImmune Way, Gaithersburg, MD, 20878, USA.
Protein Expr Purif ; 167: 105528, 2020 03.
Article en En | MEDLINE | ID: mdl-31689498

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades Autoinmunes / Receptor de Interferón alfa y beta Límite: Animals / Humans Idioma: En Revista: Protein Expr Purif Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades Autoinmunes / Receptor de Interferón alfa y beta Límite: Animals / Humans Idioma: En Revista: Protein Expr Purif Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article