Axo-glial interdependence in peripheral nerve development.
Development
; 146(21)2019 11 12.
Article
en En
| MEDLINE
| ID: mdl-31719044
During the development of the peripheral nervous system, axons and myelinating Schwann cells form a unique symbiotic unit, which is realized by a finely tuned network of molecular signals and reciprocal interactions. The importance of this complex interplay becomes evident after injury or in diseases in which aspects of axo-glial interaction are perturbed. This Review focuses on the specific interdependence of axons and Schwann cells in peripheral nerve development that enables axonal outgrowth, Schwann cell lineage progression, radial sorting and, finally, formation and maintenance of the myelin sheath.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Nervios Periféricos
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Células de Schwann
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Axones
/
Neuroglía
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Regulación del Desarrollo de la Expresión Génica
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Vaina de Mielina
Límite:
Animals
Idioma:
En
Revista:
Development
Asunto de la revista:
BIOLOGIA
/
EMBRIOLOGIA
Año:
2019
Tipo del documento:
Article