Your browser doesn't support javascript.
loading
Axo-glial interdependence in peripheral nerve development.
Fledrich, Robert; Kungl, Theresa; Nave, Klaus-Armin; Stassart, Ruth M.
Afiliación
  • Fledrich R; Institute of Anatomy, Leipzig University, 04103 Leipzig, Germany Robert.Fledrich@medizin.uni-leipzig.de Ruth.Stassart@medizin.uni-leipzig.de.
  • Kungl T; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.
  • Nave KA; Institute of Anatomy, Leipzig University, 04103 Leipzig, Germany.
  • Stassart RM; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.
Development ; 146(21)2019 11 12.
Article en En | MEDLINE | ID: mdl-31719044
During the development of the peripheral nervous system, axons and myelinating Schwann cells form a unique symbiotic unit, which is realized by a finely tuned network of molecular signals and reciprocal interactions. The importance of this complex interplay becomes evident after injury or in diseases in which aspects of axo-glial interaction are perturbed. This Review focuses on the specific interdependence of axons and Schwann cells in peripheral nerve development that enables axonal outgrowth, Schwann cell lineage progression, radial sorting and, finally, formation and maintenance of the myelin sheath.
Asunto(s)
Palabras clave

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Nervios Periféricos / Células de Schwann / Axones / Neuroglía / Regulación del Desarrollo de la Expresión Génica / Vaina de Mielina Límite: Animals Idioma: En Revista: Development Asunto de la revista: BIOLOGIA / EMBRIOLOGIA Año: 2019 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Nervios Periféricos / Células de Schwann / Axones / Neuroglía / Regulación del Desarrollo de la Expresión Génica / Vaina de Mielina Límite: Animals Idioma: En Revista: Development Asunto de la revista: BIOLOGIA / EMBRIOLOGIA Año: 2019 Tipo del documento: Article