Novel cell-permeable p38-MAPK inhibitor efficiently prevents porcine islet apoptosis and improves islet graft function.

Noguchi, Hirofumi; Miyagi-Shiohira, Chika; Nakashima, Yoshiki; Saitoh, Issei; Watanabe, Masami

Noguchi, Hirofumi; Miyagi-Shiohira, Chika; Nakashima, Yoshiki; Saitoh, Issei; Watanabe, Masami.

Afiliación

Noguchi H; Department of Regenerative Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Miyagi-Shiohira C; Department of Regenerative Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Nakashima Y; Department of Regenerative Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Saitoh I; Division of Pediatric Dentistry, Graduate School of Medical and Dental Science, Niigata University, Niigata, Japan.
Watanabe M; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

Am J Transplant ; 20(5): 1296-1308, 2020 05.

Article en En | MEDLINE | ID: mdl-31834983

Asunto(s)

Diabetes Mellitus Experimental; Trasplante de Islotes Pancreáticos; Islotes Pancreáticos; Animales; Apoptosis; Diabetes Mellitus Experimental/tratamiento farmacológico; Ratones; Porcinos; Proteínas Quinasas p38 Activadas por Mitógenos

Palabras clave

basic (laboratory) research/science; cell death: apoptosis; islet isolation; islet transplantation

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Trasplante de Islotes Pancreáticos / Islotes Pancreáticos / Diabetes Mellitus Experimental Límite: Animals Idioma: En Revista: Am J Transplant Asunto de la revista: TRANSPLANTE Año: 2020 Tipo del documento: Article País de afiliación: Japón

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