Osteoclast-derived miR-23a-5p-containing exosomes inhibit osteogenic differentiation by regulating Runx2.

Yang, Jun-Xiao; Xie, Peng; Li, Yu-Sheng; Wen, Ting; Yang, Xu-Cheng

Yang, Jun-Xiao; Xie, Peng; Li, Yu-Sheng; Wen, Ting; Yang, Xu-Cheng.

Afiliación

Yang JX; Department of orthopedics, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, PR China.
Xie P; Department of orthopedics, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, PR China.
Li YS; Department of orthopedics, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, PR China.
Wen T; Department of orthopedics, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, PR China.
Yang XC; Department of orthopedics, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, PR China. Electronic address: yangxucheng5156@163.com.

Cell Signal ; 70: 109504, 2020 06.

Article en En | MEDLINE | ID: mdl-31857240

Asunto(s)

Subunidad alfa 1 del Factor de Unión al Sitio Principal/metabolismo; Exosomas/metabolismo; MicroARNs/metabolismo; Osteoclastos/metabolismo; Osteogénesis; Proteínas Adaptadoras Transductoras de Señales/metabolismo; Animales; Diferenciación Celular; Humanos; Ratones; Osteoblastos/citología; Osteoblastos/metabolismo; Osteoclastos/citología; Células RAW 264.7; Proteínas Señalizadoras YAP

Palabras clave

Exosomes; Osteoclast; Osteogenic differentiation; Runx2; miR-23a-5p

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Osteoclastos / Osteogénesis / MicroARNs / Subunidad alfa 1 del Factor de Unión al Sitio Principal / Exosomas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Signal Año: 2020 Tipo del documento: Article

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