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Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice.
Wenzel, Jan; Hansen, Cathrin E; Bettoni, Carla; Vogt, Miriam A; Lembrich, Beate; Natsagdorj, Rentsenkhand; Huber, Gianna; Brands, Josefine; Schmidt, Kjestine; Assmann, Julian C; Stölting, Ines; Saar, Kathrin; Sedlacik, Jan; Fiehler, Jens; Ludewig, Peter; Wegmann, Michael; Feller, Nina; Richter, Marius; Müller-Fielitz, Helge; Walther, Thomas; König, Gabriele M; Kostenis, Evi; Raasch, Walter; Hübner, Norbert; Gass, Peter; Offermanns, Stefan; de Wit, Cor; Wagner, Carsten A; Schwaninger, Markus.
Afiliación
  • Wenzel J; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany; jan.wenzel@uni-luebeck.de markus.schwaninger@uni-luebeck.de.
  • Hansen CE; DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562 Lübeck, Germany.
  • Bettoni C; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.
  • Vogt MA; Institute of Physiology, University of Zürich, CH-8057 Zürich, Switzerland.
  • Lembrich B; Central Institute of Mental Health, Medical Faculty of Mannheim/University of Heidelberg, 68159 Mannheim, Germany.
  • Natsagdorj R; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.
  • Huber G; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.
  • Brands J; DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562 Lübeck, Germany.
  • Schmidt K; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.
  • Assmann JC; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.
  • Stölting I; DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562 Lübeck, Germany.
  • Saar K; DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562 Lübeck, Germany.
  • Sedlacik J; Institute of Physiology, University of Lübeck, 23562 Lübeck, Germany.
  • Fiehler J; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.
  • Ludewig P; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.
  • Wegmann M; Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany.
  • Feller N; DZHK (German Research Centre for Cardiovascular Research), partner site Berlin, 13125 Berlin, Germany.
  • Richter M; Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
  • Müller-Fielitz H; Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
  • Walther T; Department of Neurology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
  • König GM; Priority Area Asthma and Allergy, Research Center Borstel, 23845 Borstel, Germany.
  • Kostenis E; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.
  • Raasch W; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.
  • Hübner N; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.
  • Gass P; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.
  • Offermanns S; Institute for Pharmaceutical Biology, University of Bonn, 53115 Bonn, Germany.
  • de Wit C; Institute for Pharmaceutical Biology, University of Bonn, 53115 Bonn, Germany.
  • Wagner CA; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, 23562 Lübeck, Germany.
  • Schwaninger M; DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, 23562 Lübeck, Germany.
Proc Natl Acad Sci U S A ; 117(3): 1753-1761, 2020 01 21.
Article en En | MEDLINE | ID: mdl-31896584
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ansiedad / Trastornos Respiratorios / Sistema Cardiovascular / Endotelio Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ansiedad / Trastornos Respiratorios / Sistema Cardiovascular / Endotelio Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article