Accelerated osteoblastic differentiation in patient-derived dental pulp stem cells carrying a gain-of-function mutation of TRPV4 associated with metatropic dysplasia.

Han, Xu; Kato, Hiroki; Sato, Hiroshi; Hirofuji, Yuta; Fukumoto, Satoshi; Masuda, Keiji

Han, Xu; Kato, Hiroki; Sato, Hiroshi; Hirofuji, Yuta; Fukumoto, Satoshi; Masuda, Keiji.

Afiliación

Han X; Section of Oral Medicine for Children, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Maidashi 3-1-1, Higashi-Ku, Fukuoka, 812-8582, Japan.
Kato H; Section of Oral Medicine for Children, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Maidashi 3-1-1, Higashi-Ku, Fukuoka, 812-8582, Japan.
Sato H; Section of Oral Medicine for Children, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Maidashi 3-1-1, Higashi-Ku, Fukuoka, 812-8582, Japan.
Hirofuji Y; Section of Oral Medicine for Children, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Maidashi 3-1-1, Higashi-Ku, Fukuoka, 812-8582, Japan.
Fukumoto S; Section of Oral Medicine for Children, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Maidashi 3-1-1, Higashi-Ku, Fukuoka, 812-8582, Japan. Electronic address: fukumoto@dent.kyushu-u.ac.jp.
Masuda K; Section of Oral Medicine for Children, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Maidashi 3-1-1, Higashi-Ku, Fukuoka, 812-8582, Japan. Electronic address: kemasuda@dent.kyushu-u.ac.jp.

Biochem Biophys Res Commun ; 523(4): 841-846, 2020 03 19.

Article en En | MEDLINE | ID: mdl-31954514

Asunto(s)

Diferenciación Celular; Pulpa Dental/patología; Enanismo/genética; Mutación con Ganancia de Función/genética; Osteoblastos/metabolismo; Osteoblastos/patología; Osteocondrodisplasias/genética; Células Madre/metabolismo; Canales Catiónicos TRPV/genética; Adolescente; Calcio/metabolismo; Humanos; Espacio Intracelular/metabolismo; Factores de Transcripción NFATC/metabolismo; Transducción de Señal

Palabras clave

Dental pulp stem cells; Metatropic dysplasia; Osteoblast differentiation; Transient receptor potential vanilloid 4

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Osteoblastos / Osteocondrodisplasias / Células Madre / Diferenciación Celular / Pulpa Dental / Enanismo / Canales Catiónicos TRPV / Mutación con Ganancia de Función Tipo de estudio: Risk_factors_studies Límite: Adolescent / Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 2020 Tipo del documento: Article País de afiliación: Japón

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