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Hyperactivation of TORC1 Drives Resistance to the Pan-HER Tyrosine Kinase Inhibitor Neratinib in HER2-Mutant Cancers.
Sudhan, Dhivya R; Guerrero-Zotano, Angel; Won, Helen; González Ericsson, Paula; Servetto, Alberto; Huerta-Rosario, Mariela; Ye, Dan; Lee, Kyung-Min; Formisano, Luigi; Guo, Yan; Liu, Qi; Kinch, Lisa N; Red Brewer, Monica; Dugger, Teresa; Koch, James; Wick, Michael J; Cutler, Richard E; Lalani, Alshad S; Bryce, Richard; Auerbach, Alan; Hanker, Ariella B; Arteaga, Carlos L.
Afiliación
  • Sudhan DR; Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Guerrero-Zotano A; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Won H; Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • González Ericsson P; Breast Cancer Program, Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
  • Servetto A; Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Huerta-Rosario M; Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Ye D; Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Lee KM; Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Formisano L; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Guo Y; Comprehensive Cancer Center, University of New Mexico, Albuquerque, NM, USA.
  • Liu Q; Center for Quantitative Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Kinch LN; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Red Brewer M; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Dugger T; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Koch J; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Wick MJ; START, 4383 Medical Drive, San Antonio, TX, USA.
  • Cutler RE; Puma Biotechnology, Inc., Los Angeles, CA, USA.
  • Lalani AS; Puma Biotechnology, Inc., Los Angeles, CA, USA.
  • Bryce R; Puma Biotechnology, Inc., Los Angeles, CA, USA.
  • Auerbach A; Puma Biotechnology, Inc., Los Angeles, CA, USA.
  • Hanker AB; Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address: ariella.hanker@utsouthwestern.edu.
  • Arteaga CL; Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address: carlos.arteaga@utsouthwestern.edu.
Cancer Cell ; 37(2): 183-199.e5, 2020 02 10.
Article en En | MEDLINE | ID: mdl-31978326
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quinolinas / Neoplasias de la Mama / Resistencia a Antineoplásicos / Diana Mecanicista del Complejo 1 de la Rapamicina Límite: Humans Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
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Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quinolinas / Neoplasias de la Mama / Resistencia a Antineoplásicos / Diana Mecanicista del Complejo 1 de la Rapamicina Límite: Humans Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos