Transposon Mutagenesis Screen of Klebsiella pneumoniae Identifies Multiple Genes Important for Resisting Antimicrobial Activities of Neutrophils in Mice.

Paczosa, Michelle K; Silver, Rebecca J; McCabe, Anne L; Tai, Albert K; McLeish, Colin H; Lazinski, David W; Mecsas, Joan

Paczosa, Michelle K; Silver, Rebecca J; McCabe, Anne L; Tai, Albert K; McLeish, Colin H; Lazinski, David W; Mecsas, Joan.

Afiliación

Paczosa MK; Graduate Program in Immunology, MERGE-ID Track, Graduate School of Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, USA.
Silver RJ; Graduate Program in Immunology, MERGE-ID Track, Graduate School of Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, USA.
McCabe AL; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Tai AK; Department of Immunology, Tufts University School of Medicine, Boston, Massachusetts, USA.
McLeish CH; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Lazinski DW; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Mecsas J; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA Joan.mecsas@tufts.edu.

Infect Immun ; 88(4)2020 03 23.

Article en En | MEDLINE | ID: mdl-31988174

Asunto(s)

Interacciones Huésped-Patógeno; Infecciones por Klebsiella/inmunología; Klebsiella pneumoniae/inmunología; Neutrófilos/inmunología; Neutrófilos/microbiología; Neumonía Bacteriana/inmunología; Factores de Virulencia/metabolismo; Animales; Elementos Transponibles de ADN; Modelos Animales de Enfermedad; Pruebas Genéticas; Infecciones por Klebsiella/microbiología; Klebsiella pneumoniae/genética; Ratones; Mutagénesis Insercional; Neumonía Bacteriana/microbiología; Virulencia; Factores de Virulencia/genética

Palabras clave

Klebsiella; Klebsiella pneumoniae; Tn-seq; dedA; gntR; lung infection; neutropenia; wzm; yaaA; ycgE

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Infecciones por Klebsiella / Neumonía Bacteriana / Factores de Virulencia / Interacciones Huésped-Patógeno / Klebsiella pneumoniae / Neutrófilos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Infect Immun Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

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