Assessing the Autonomic and Behavioral Effects of Passive Motion in Rats using Elevator Vertical Motion and Ferris-Wheel Rotation.
J Vis Exp
; (156)2020 02 07.
Article
en En
| MEDLINE
| ID: mdl-32091010
ABSTRACT
The overall goal of this study is to assess the autonomic and behavioral effects of passive motion in rodents using the elevator vertical motion and Ferris-wheel rotation devices. These assays can help confirm the integrity and normal functioning of the autonomic nervous system. They are coupled to quantitative measures based on defecation counting, open-field examination, and balance beam crossing. The advantages of these assays are their simplicity, reproducibility, and quantitative behavioral measures. The limitations of these assays are that the autonomic reactions could be epiphenomena of non-vestibular disorders and that a functioning vestibular system is required. Examination of disorders such as motion sickness will be greatly aided by the detailed procedures of these assays.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Rotación
/
Sistema Nervioso Autónomo
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Conducta Animal
/
Ascensores y Escaleras Mecánicas
Límite:
Animals
Idioma:
En
Revista:
J Vis Exp
Año:
2020
Tipo del documento:
Article