Suppressing STAT5 signaling affects osteosarcoma growth and stemness.

Subramaniam, Dharmalingam; Angulo, Pablo; Ponnurangam, Sivapriya; Dandawate, Prasad; Ramamoorthy, Prabhu; Srinivasan, Pugazhendhi; Iwakuma, Tomoo; Weir, Scott J; Chastain, Katherine; Anant, Shrikant

Subramaniam, Dharmalingam; Angulo, Pablo; Ponnurangam, Sivapriya; Dandawate, Prasad; Ramamoorthy, Prabhu; Srinivasan, Pugazhendhi; Iwakuma, Tomoo; Weir, Scott J; Chastain, Katherine; Anant, Shrikant.

Afiliación

Subramaniam D; Department of Cancer Biology, The University of Kansas Medical Center, Kansas City, KS, 66160, USA.
Angulo P; Division of Hematology and Oncology, Children's Mercy Hospital, Kansas City, MO, 64108, USA.
Ponnurangam S; Banner Health, 1432S. Dobson Rd. Ste. 107, Mesa, AZ, 85202, USA.
Dandawate P; Department of Cancer Biology, The University of Kansas Medical Center, Kansas City, KS, 66160, USA.
Ramamoorthy P; Department of Cancer Biology, The University of Kansas Medical Center, Kansas City, KS, 66160, USA.
Srinivasan P; Department of Cancer Biology, The University of Kansas Medical Center, Kansas City, KS, 66160, USA.
Iwakuma T; Department of Cancer Biology, The University of Kansas Medical Center, Kansas City, KS, 66160, USA.
Weir SJ; Department of Cancer Biology, The University of Kansas Medical Center, Kansas City, KS, 66160, USA.
Chastain K; Division of Hematology and Oncology, Children's Mercy Hospital, Kansas City, MO, 64108, USA.
Anant S; Department of Cancer Biology, The University of Kansas Medical Center, Kansas City, KS, 66160, USA.

Cell Death Dis ; 11(2): 149, 2020 02 24.

Article en En | MEDLINE | ID: mdl-32094348

Asunto(s)

Osteosarcoma/tratamiento farmacológico; Pimozida/farmacología; Factor de Transcripción STAT5/farmacología; Proteínas Supresoras de Tumor/farmacología; Animales; Apoptosis/efectos de los fármacos; Proliferación Celular/efectos de los fármacos; Puntos de Control de la Fase G1 del Ciclo Celular/efectos de los fármacos; Humanos; Células Madre Neoplásicas/efectos de los fármacos; Células Madre Neoplásicas/metabolismo; Osteosarcoma/metabolismo; Factor de Transcripción STAT5/efectos de los fármacos; Factor de Transcripción STAT5/metabolismo; Transducción de Señal/efectos de los fármacos

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pimozida / Osteosarcoma / Proteínas Supresoras de Tumor / Factor de Transcripción STAT5 Límite: Animals / Humans Idioma: En Revista: Cell Death Dis Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

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