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NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly.
He, Feng; Antonucci, Laura; Yamachika, Shinichiro; Zhang, Zechuan; Taniguchi, Koji; Umemura, Atsushi; Hatzivassiliou, Georgia; Roose-Girma, Merone; Reina-Campos, Miguel; Duran, Angeles; Diaz-Meco, Maria T; Moscat, Jorge; Sun, Beicheng; Karin, Michael.
Afiliación
  • He F; Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Antonucci L; Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Yamachika S; Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Zhang Z; Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing 210008, Jiangsu Province, China.
  • Taniguchi K; Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Umemura A; Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
  • Hatzivassiliou G; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Roose-Girma M; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Reina-Campos M; Cancer Metabolism and Signaling Networks Program, Sanford-Burnham-Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Duran A; Cancer Metabolism and Signaling Networks Program, Sanford-Burnham-Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Diaz-Meco MT; Cancer Metabolism and Signaling Networks Program, Sanford-Burnham-Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Moscat J; Cancer Metabolism and Signaling Networks Program, Sanford-Burnham-Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Sun B; Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing 210008, Jiangsu Province, China. Electronic address: sunbc@nju.edu.cn.
  • Karin M; Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA; Department of Pathology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address: karinoffice@
J Hepatol ; 72(6): 1182-1195, 2020 06.
Article en En | MEDLINE | ID: mdl-32105670
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad Veno-Oclusiva Hepática / Genes erbB-1 / Hepatitis Autoinmune / Proteínas Proto-Oncogénicas c-akt / Factor 2 Relacionado con NF-E2 / Receptores ErbB / Hepatomegalia Tipo de estudio: Prognostic_studies Límite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad Veno-Oclusiva Hepática / Genes erbB-1 / Hepatitis Autoinmune / Proteínas Proto-Oncogénicas c-akt / Factor 2 Relacionado con NF-E2 / Receptores ErbB / Hepatomegalia Tipo de estudio: Prognostic_studies Límite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos