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Structure-based discovery of potent and selective melatonin receptor agonists.
Patel, Nilkanth; Huang, Xi Ping; Grandner, Jessica M; Johansson, Linda C; Stauch, Benjamin; McCorvy, John D; Liu, Yongfeng; Roth, Bryan; Katritch, Vsevolod.
Afiliación
  • Patel N; Department of Biological Sciences and Department of Chemistry, Bridge Institute, USC Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, United States.
  • Huang XP; Department of Pharmacology, University of North Carolina Chapel Hill Medical School, Chapel Hill, United States.
  • Grandner JM; National Institute of Mental Health Psychoactive Drug Screening Program, Department of Pharmacology, University of North Carolina Chapel Hill Medical School, Chapel Hill, United States.
  • Johansson LC; Department of Biological Sciences and Department of Chemistry, Bridge Institute, USC Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, United States.
  • Stauch B; Department of Biological Sciences and Department of Chemistry, Bridge Institute, USC Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, United States.
  • McCorvy JD; Department of Biological Sciences and Department of Chemistry, Bridge Institute, USC Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, United States.
  • Liu Y; Department of Pharmacology, University of North Carolina Chapel Hill Medical School, Chapel Hill, United States.
  • Roth B; National Institute of Mental Health Psychoactive Drug Screening Program, Department of Pharmacology, University of North Carolina Chapel Hill Medical School, Chapel Hill, United States.
  • Katritch V; Department of Pharmacology, University of North Carolina Chapel Hill Medical School, Chapel Hill, United States.
Elife ; 92020 03 02.
Article en En | MEDLINE | ID: mdl-32118583

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores de Melatonina / Descubrimiento de Drogas Límite: Humans Idioma: En Revista: Elife Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores de Melatonina / Descubrimiento de Drogas Límite: Humans Idioma: En Revista: Elife Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos