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A mitochondria-targeted fluorescent probe for hypochlorite sensing and its application in bioimaging.
Yang, Qing; Zhong, Xiuli; Chen, Yingshuang; Yang, Jing; Jin, Can; Jiang, Yuliang.
Afiliación
  • Yang Q; Nanjing Normal University, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing 210023, Jiangsu, P. R. China. 07174@njnu.edu.cn 07205@njnu.edu.cn.
  • Zhong X; Nanjing Normal University, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing 210023, Jiangsu, P. R. China. 07174@njnu.edu.cn 07205@njnu.edu.cn.
  • Chen Y; Nanjing Normal University, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing 210023, Jiangsu, P. R. China. 07174@njnu.edu.cn 07205@njnu.edu.cn.
  • Yang J; Nanjing Normal University, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing 210023, Jiangsu, P. R. China. 07174@njnu.edu.cn 07205@njnu.edu.cn.
  • Jin C; Institute of Chemical Industry of Forest Products, Jiangsu Provincial Key Laboratory of Biomass Energy and Materials, National Engineering Laboratory for Biomass Chemical Utilization, CAF, Nanjing 210042, Jiangsu, P. R. China. envis@163.com.
  • Jiang Y; Nanjing Normal University, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing 210023, Jiangsu, P. R. China. 07174@njnu.edu.cn 07205@njnu.edu.cn.
Analyst ; 145(8): 3100-3105, 2020 Apr 14.
Article en En | MEDLINE | ID: mdl-32150184
A coumarin-diaminomaleonitrile derivative (C-DAN) was designed and prepared. Upon addition of hypochlorite (OCl-), the fluorescence emission peak of C-DAN at 475 nm was gradually enhanced with a rapid response (within 5 s); meanwhile, the color of the solution changed from dark red to bright yellow which can be observed with the naked eye. Furthermore, owing to its advantages including high selectivity, sensitivity, and low toxicity, our C-DAN probe has been applied for detecting OCl- in living cells and zebrafish, indicating it is an ideal tool for biological applications.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ácido Hipocloroso / Cumarinas / Colorantes Fluorescentes / Mitocondrias / Nitrilos Límite: Animals / Humans Idioma: En Revista: Analyst Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ácido Hipocloroso / Cumarinas / Colorantes Fluorescentes / Mitocondrias / Nitrilos Límite: Animals / Humans Idioma: En Revista: Analyst Año: 2020 Tipo del documento: Article