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A pyruvate dehydrogenase kinase inhibitor prevents retinal cell death and improves energy metabolism in rat retinas after ischemia/reperfusion injury.
Sato, Kota; Mochida, Seiya; Tomimoto, Daisuke; Konuma, Takahiro; Kiyota, Naoki; Tsuda, Satoru; Shiga, Yukihiro; Omodaka, Kazuko; Nakazawa, Toru.
Afiliación
  • Sato K; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Miyagi, Japan; Collaborative Program for Ophthalmic Drug Discovery, Tohoku University Graduate School of Medicine, Miyagi, Japan.
  • Mochida S; Biological/Pharmacological Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., 1-1 Murasaki-cho, Takatsuki, Osaka, Japan.
  • Tomimoto D; Biological/Pharmacological Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., 1-1 Murasaki-cho, Takatsuki, Osaka, Japan.
  • Konuma T; Biological/Pharmacological Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., 1-1 Murasaki-cho, Takatsuki, Osaka, Japan.
  • Kiyota N; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
  • Tsuda S; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
  • Shiga Y; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
  • Omodaka K; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
  • Nakazawa T; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Miyagi, Japan; Collaborative Program for Ophthalmic Drug Discovery, Tohoku University Graduate School of Medicine, Miyagi, Japan; Department of Retinal Disease Control, Tohoku University Graduate School of Medicine, Miyagi,
Exp Eye Res ; 193: 107997, 2020 04.
Article en En | MEDLINE | ID: mdl-32165157
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades de la Retina / Células Ganglionares de la Retina / Daño por Reperfusión / Metabolismo Energético / Piruvato Deshidrogenasa Quinasa Acetil-Transferidora Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Exp Eye Res Año: 2020 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades de la Retina / Células Ganglionares de la Retina / Daño por Reperfusión / Metabolismo Energético / Piruvato Deshidrogenasa Quinasa Acetil-Transferidora Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Exp Eye Res Año: 2020 Tipo del documento: Article País de afiliación: Japón