An agent-based model to investigate microbial initiation of Alzheimer's via the olfactory system.

Sundar, Shalini; Battistoni, Carly; McNulty, Ryan; Morales, Fernando; Gorky, Jonathan; Foley, Henry; Dhurjati, Prasad

Sundar, Shalini; Battistoni, Carly; McNulty, Ryan; Morales, Fernando; Gorky, Jonathan; Foley, Henry; Dhurjati, Prasad.

Afiliación

Sundar S; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA.
Battistoni C; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA.
McNulty R; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA.
Morales F; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA.
Gorky J; Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
Foley H; New York Institute of Technology, New York, NY, USA.
Dhurjati P; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA. dhurjati@udel.edu.

Theor Biol Med Model ; 17(1): 5, 2020 04 15.

Article en En | MEDLINE | ID: mdl-32290858

Asunto(s)

Enfermedad de Alzheimer; Chlamydophila pneumoniae; Ovillos Neurofibrilares; Bulbo Olfatorio; Análisis de Sistemas; Enfermedad de Alzheimer/metabolismo; Enfermedad de Alzheimer/microbiología; Enfermedad de Alzheimer/patología; Péptidos beta-Amiloides/metabolismo; Corteza Cerebral; Chlamydophila pneumoniae/patogenicidad; Humanos; Ovillos Neurofibrilares/metabolismo; Bulbo Olfatorio/metabolismo; Placa Amiloide/metabolismo

Palabras clave

Agent-based model; Alzheimer's disease; Biological modelling framework; Microbiome; NetLogo3-D; Olfactory system

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Bulbo Olfatorio / Análisis de Sistemas / Ovillos Neurofibrilares / Chlamydophila pneumoniae / Enfermedad de Alzheimer Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Theor Biol Med Model Asunto de la revista: BIOLOGIA / MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

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